1429184-75-7Relevant articles and documents
Synthesis, cyclooxygenase inhibitory effects, and molecular modeling study of 4-aryl-5-(4-(methylsulfonyl)phenyl)-2-alkylthio and -2-alkylsulfonyl-1H- imidazole derivatives
Assadieskandar, Amir,Amirhamzeh, Amirali,Salehi, Marjan,Ozadali, Keriman,Ostad, Seyed Nasser,Shafiee, Abbas,Amini, Mohsen
, p. 2355 - 2362 (2013/05/23)
A series of 4-aryl-5-(4-(methylsulfonyl)phenyl)-2-alkylthio and 2-alkylsulfonyl-1H-imidazole derivatives were synthesized. All compounds were tested in human blood assay to determine COX-1 and COX-2 inhibitory potency and selectivity. Among the synthesize