1433204-54-6

Basic information

• Product Name: (±)-O-(triisopropylsilyl)laudanidine
• Synonyms: (±)-O-(triisopropylsilyl)laudanidine
• CAS NO: 1433204-54-6
• Molecular Weight: 499.766
• Mol File: 1433204-54-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (±)-O-(triisopropylsilyl)laudanidine(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-O-(triisopropylsilyl)laudanidine(1433204-54-6)
• EPA Substance Registry System: (±)-O-(triisopropylsilyl)laudanidine(1433204-54-6)

Safety Data

• Hazardous Substances Data: 1433204-54-6(Hazardous Substances Data)

Downstream Products

• 85-64-3 laudanine 

Relevant articles and documents

Synthesis of alkaloids by stevens rearrangement of nitrile-stabilized ammonium ylides: (±)-laudanosine, (±)-laudanidine, (±)-armepavine, (±)-7-methoxycryptopleurine, and (±)-xylopinine

The Stevens rearrangement of nitrile-stabilized ammonium ylides in conjunction with the reductive removal of the nitrile function permits the facile construction of α-branched amines from α-aminonitriles. We employed this reaction sequence for the preparation of (±)-laudanosine, (±)-laudanidine and (±)-armepavine, (±)-7- methoxycryptopleurine, and (±)-xylopinine from two closely related and readily accessible bicyclic α-aminonitriles. The final products were obtained in high to almost quantitative yields (71-98%) from the quaternary ammonium salts obtained by N-alkylation of these starting materials.