143613-14-3

Basic information

• Product Name: Benzoic acid, 2-(2-methyl-1,3-dioxolan-2-yl)-6-(phenylmethoxy)-, methyl ester
• CAS NO: 143613-14-3
• Molecular Formula: C19H20O5
• Molecular Weight: 328.365
• Mol File: 143613-14-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(2-methyl-1,3-dioxolan-2-yl)-6-(phenylmethoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(2-methyl-1,3-dioxolan-2-yl)-6-(phenylmethoxy)-, methyl ester(143613-14-3)
• EPA Substance Registry System: Benzoic acid, 2-(2-methyl-1,3-dioxolan-2-yl)-6-(phenylmethoxy)-, methyl ester(143613-14-3)

Safety Data

• Hazardous Substances Data: 143613-14-3(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 121-71-1 3-Hydroxyacetophenone 
• 34068-01-4 1-[3-(phenylmethoxy)phenyl]ethan-1-one 
• 79-22-1 methyl chloroformate 
• 143613-10-9 2-[3-(benzyloxy)phenyl]-2-methyl-1,3-dioxolane 

Downstream Products

• 136192-85-3 methyl 1-hydroxy-6-acetylbenzoate 
• 150314-88-8 methyl 2-(4,6-dimethoxypyrimidin-2-yloxy)-6-(2-methyl-1,3-dioxolan-2-yl)benzoate 
• 136192-67-1 Methyl 2-acetyl-6-[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate 
• 155134-69-3 2-Acetyl-6-benzyloxy-benzoic acid methyl ester 
• 147411-62-9 methyl 2-hydroxy-6-(2-methyl-1,3-dioxolan-2-yl)benzoate 

Relevant articles and documents

Design and syntheses of novel phthalazin-1(2H)-one derivatives as acetohydroxyacid synthase inhibitors

A series of 2-substituted-8-(4,6-dimethoxypyrimidin-2-yloxy)-4- methylphthalazin-1-one derivatives, 7a-7w, were designed via an ortho-substituent cyclization strategy to discover a new herbicidal lead structure. These compounds were synthesized by a seven-step route using 3-hydroxy-acetophenone as a starting material. Determination of the K i values against wild-type A. thaliana acetohydroxyacid synthase (AHAS) (EC 4.1.3.18) indicated that some of the compounds displayed good enzyme inhibition activity comparable to that of KIH-6127. The further preliminary bioassay data on weeds showed that the synthesized compounds exhibited typical injury symptoms of AHAS-inhibiting herbicides, and some of them showed broad-spectrum and high herbicidal activities in postemergence treatments against Echinochloa crusgalli, Digitaria sanguinalis, Setaria viridis, Brassica juncea, Amaranthus retroflexus, and Chenopodium album at an application rate of 150 g ai/ha. To our knowledge, this is the first report of methylphthalazin-1- one derivatives as AHAS inhibitors.