1437717-61-7

Basic information

• Product Name: (R)-2-[2-(2-chloro-5-methoxy-4-nitro-phenyl)-ethylcarbamoyl]-morpholine-4-carboxylic acid tert-butyl ester
• Synonyms: (R)-2-[2-(2-chloro-5-methoxy-4-nitro-phenyl)-ethylcarbamoyl]-morpholine-4-carboxylic acid tert-butyl ester
• CAS NO: 1437717-61-7
• Molecular Weight: 443.884
• Mol File: 1437717-61-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-[2-(2-chloro-5-methoxy-4-nitro-phenyl)-ethylcarbamoyl]-morpholine-4-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-[2-(2-chloro-5-methoxy-4-nitro-phenyl)-ethylcarbamoyl]-morpholine-4-carboxylic acid tert-butyl ester(1437717-61-7)
• EPA Substance Registry System: (R)-2-[2-(2-chloro-5-methoxy-4-nitro-phenyl)-ethylcarbamoyl]-morpholine-4-carboxylic acid tert-butyl ester(1437717-61-7)

Safety Data

• Hazardous Substances Data: 1437717-61-7(Hazardous Substances Data)

Upstream product

• 1349744-81-5 1-chloro-4-methoxy-5-nitro-2-vinylbenzene 
• 1360616-77-8 1-bromo-2-chloro-5-methoxy-4-nitro-benzene 
• 884512-77-0 (R)-4-(tert-butyloxycarbonyl)morpholine-2-carboxylic acid 
• 1437717-53-7 2-(2-chloro-5-methoxy-4-nitro-phenyl)-ethylamine 
• 201849-15-2 2-bromo-1-chloro-4-fluoro-benzene 
• 1437717-45-7 [2-(2-chloro-5-methoxy-4-nitro-phenyl)-ethyl]-(2,4-dimethoxy-benzyl)-amine 
• 1027833-17-5 1-bromo-2-chloro-5-fluoro-4-nitrobenzene 

Downstream Products

• 1437717-69-5 (R)-2-[2-(4-amino-2-chloro-5-methoxy-phenyl)-ethylcarbamoyl]-morpholine-4-carboxylic acid tert-butyl ester 
• 1437717-77-5 (R)-2-(2-{2-chloro-4-[3-(5-cyano-pyrazin-2-yl)-ureido]-5-methoxy-phenyl}-ethylcarbamoyl)-morpholine-4-carboxylic acid tert-butyl ester 

Relevant articles and documents

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The invention provides compounds which inhibit or modulate the activity of Chk-1 kinase and which are useful in the treatment of cancer. The compounds have the general formula (1): and salts, N-oxides and tautomers thereof, wherein m is 2, 3 or 4; n is 0