1443037-88-4

Basic information

• Product Name: 4-chloro-benzoic acid 2-chloro-6-fluoro-phenyl ester
• Synonyms: 4-chloro-benzoic acid 2-chloro-6-fluoro-phenyl ester
• CAS NO: 1443037-88-4
• Molecular Weight: 285.102
• Mol File: 1443037-88-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-chloro-benzoic acid 2-chloro-6-fluoro-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-benzoic acid 2-chloro-6-fluoro-phenyl ester(1443037-88-4)
• EPA Substance Registry System: 4-chloro-benzoic acid 2-chloro-6-fluoro-phenyl ester(1443037-88-4)

Safety Data

• Hazardous Substances Data: 1443037-88-4(Hazardous Substances Data)

Upstream product

• 2040-90-6 2-chloro-6-fluorophenol 
• 122-01-0 4-chloro-benzoyl chloride 

Downstream Products

• 1443037-93-1 (3-chloro-5-fluoro-4-hydroxy-phenyl)-(4-chloro-phenyl)-methanone 
• 1443037-98-6 [2-chloro-4-(4-chloro-benzoyl)-6-fluoro-phenoxy]-acetic acid ethyl ester 
• 1443038-13-8 C₃₀H₁₈Cl₃F₃N₂O₆ 
• 1443038-17-2 C₃₀H₁₈Cl₄F₂N₂O₆ 
• 1443038-18-3 C₃₁H₂₁Cl₃F₂N₂O₆ 
• 1443038-19-4 C₃₀H₁₈Cl₃F₂IN₂O₆ 
• 1443038-20-7 C₃₀H₁₈BrCl₃F₂N₂O₆ 
• 1443038-23-0 C₃₀H₁₆Cl₃F₃N₂O₅ 
• 1443038-27-4 C₃₀H₁₆Cl₄F₂N₂O₅ 
• 1443038-28-5 C₃₁H₁₉Cl₃F₂N₂O₅ 
• 1443038-29-6 C₃₀H₁₆Cl₃F₂IN₂O₅ 
• 1443038-30-9 C₃₀H₁₆BrCl₃F₂N₂O₅ 

Relevant articles and documents

Synthesis, molecular docking, and apoptogenic efficacy of novel N-heterocycle analogs to target B-cell lymphoma 2/X-linked inhibitors of apoptosis proteins to regress melanoma

The novel series of piperidine conjugated benzophenone analogs with amide link 11a–l were synthesized in a multistep process. The structures of these compounds were confirmed by IR, 1H, 13C, NMR, and mass spectra and also by elementa

Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton's lymphoma

A series of benzophenones possessing pyridine nucleus 8a-l were synthesized by multistep reaction sequence and evaluated for antiproliferative activity against DLA cells by in vitro and in vivo studies. The results suggested that, compounds 8b with fluoro group and 8e with chloro substituent at the benzoyl ring of benzophenone scaffold as well as pyridine ring with hydroxy group exhibited significant activity. Further investigation in mouse model suggests that compounds 8b and 8e have the potency to activate caspase activated DNase (endonuclease) which is responsible for DNA fragmentation, a primary hallmark of apoptosis and thereby inhibits the Dalton's lymphoma ascites tumour growth.

Synthesis and evaluation of 2,5-di(4-aryloylaryloxymethyl)-1,3,4- oxadiazoles as anti-cancer agents

A series of 2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazoles 9a-j were obtained via multistep synthesis from hydroxybenzophenones 4a-e. The cytotoxicity of compounds 9a-j was evaluated against human leukemia cell lines (K562 and CEM). The compounds exhibited moderate to good anti-cancer activity with compounds 9b and 9i having a chloro group exhibiting the best activity (IC50 = 10 μM). Compound 9i exhibited activity against both the cell lines and 9b only exhibited activity against CEM. Further, a lactate dehydrogenase (LDH) assay and DNA fragmentation studies of the compounds 9a-j were also performed.