1448444-79-8

Basic information

• Product Name: tert-butyl 4-(6-(dibenzylamino)-5-nitropyrimidin-4-ylamino)phenyl(methyl)carbamate
• Synonyms: tert-butyl 4-(6-(dibenzylamino)-5-nitropyrimidin-4-ylamino)phenyl(methyl)carbamate
• CAS NO: 1448444-79-8
• Molecular Weight: 540.622
• Mol File: 1448444-79-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(6-(dibenzylamino)-5-nitropyrimidin-4-ylamino)phenyl(methyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(6-(dibenzylamino)-5-nitropyrimidin-4-ylamino)phenyl(methyl)carbamate(1448444-79-8)
• EPA Substance Registry System: tert-butyl 4-(6-(dibenzylamino)-5-nitropyrimidin-4-ylamino)phenyl(methyl)carbamate(1448444-79-8)

Safety Data

• Hazardous Substances Data: 1448444-79-8(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 100-15-2 N-methyl(p-nitroaniline) 
• 474020-88-7 tert-butyl N-methyl-N-(4-nitrophenyl)carbamate 
• 1092522-02-5 tert-butyl N-methyl-N-(4-aminophenyl)carbamoate 
• 882272-97-1 N,N-dibenzyl-6-chloro-5-nitropyrimidine-4-amine 
• 103-49-1 dibenzylamine 

Downstream Products

• 1448444-80-1 tert-butyl 4-(5-amino-6-(dibenzylamino)pyrimidin-4-ylamino)phenyl(methyl)carbamate 
• 1448444-81-2 tert-butyl 4-(6-(dibenzylamino)-8-oxo-7H-purin-9(8H)-yl)phenyl(methyl)carbamate 
• 1448444-82-3 tert-butyl 4-(6-amino-8-oxo-7H-purin-9(8H)-yl)phenyl(methyl)carbamate 

Relevant articles and documents

PURINONE COMPOUNDS AS KINASE INHIBITORS

Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. In addition, reversible inhibitors of Btk are also described. Also disclosed are pharmaceutical compositions th