1448991-85-2

Basic information

• Product Name: Fc-CH₂NHCO-(C₆H₄)-SO₂F
• Synonyms: Fc-CH₂NHCO-(C₆H₄)-SO₂F
• CAS NO: 1448991-85-2
• Molecular Weight: 401.241
• Mol File: 1448991-85-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Fc-CH₂NHCO-(C₆H₄)-SO₂F(CAS DataBase Reference)
• NIST Chemistry Reference: Fc-CH₂NHCO-(C₆H₄)-SO₂F(1448991-85-2)
• EPA Substance Registry System: Fc-CH₂NHCO-(C₆H₄)-SO₂F(1448991-85-2)

Safety Data

• Hazardous Substances Data: 1448991-85-2(Hazardous Substances Data)

Upstream product

• 455-26-5 4-carboxybenzenesulfonyl fluoride 

Relevant articles and documents

Synthetic strategies for efficient conjugation of organometallic complexes with pendant protein reactive markers

Site-directed conjugation of metal centers to proteins is fundamental for biological and bioinorganic applications of transition metals. However, methods for the site-selective introduction of metal centers remain scarce. Herein, we present broadly applicable synthetic strategies for the conjugation of bioactive molecules with a range of organometallic complexes. Following three different synthetic strategies, we were able to synthesize a small library of metal conjugated protein markers featuring different types of protein reactive sites (epoxides, phenylphosphonates, fluorosulfonates and fluorophosphonate groups) as well as different late transition metals (iron, ruthenium, rhodium, palladium and platinum). The products were isolated in moderate to excellent yields and high purity. Furthermore, X-ray diffraction of the metalated protein markers corroborates structural integrity of the metal complex and the protein reactive site.