1450831-16-9

Basic information

• Product Name: 1-methyl-2-(4,4,4-trifluorobut-1-ynyl)benzene
• Synonyms: 1-methyl-2-(4,4,4-trifluorobut-1-ynyl)benzene
• CAS NO: 1450831-16-9
• Molecular Weight: 198.188
• Mol File: 1450831-16-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-methyl-2-(4,4,4-trifluorobut-1-ynyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-(4,4,4-trifluorobut-1-ynyl)benzene(1450831-16-9)
• EPA Substance Registry System: 1-methyl-2-(4,4,4-trifluorobut-1-ynyl)benzene(1450831-16-9)

Safety Data

• Hazardous Substances Data: 1450831-16-9(Hazardous Substances Data)

Upstream product

• 35851-37-7 3-(2-methylphenyl)-2-propyn-1-ol 
• 1178478-67-5 1-(3-chloroprop-1-ynyl)-2-methylbenzene 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 353-83-3 1,1,1-trifluoro-2-iodoethane 
• 7515-27-7 3-(2-methylphenyl)prop-2-ynoic acid 
• 421-06-7 2-bromo-1,1,1-trifluoroethane 

Relevant articles and documents

Method for preparing trifluoro-ethyl phenylacetylene compound

The invention provides a method for preparing a trifluoro-ethyl phenylacetylene compound. The method comprises the following step: in the presence of a copper catalyst, alkali and ligand, enabling potassium alkynyl trifluoroborate and tribromofluoroethane to react in a solvent, thereby obtaining the trifluoro-ethyl phenylacetylene compound. The method provided by the invention is capable of achieving high-yield synthesis of the trifluoro-ethyl phenylacetylene compound, and has good application prospects and industrial production potential.

Copper-catalyzed nucleophilic trifluoromethylation of propargylic halides

Reactions of propargylic halides with trifluoromethyltrimethylsilane in the presence of a catalytic amount of copper(i) thiophene-2-carboxylate (CuTC) have been found to give the corresponding trifluoromethylated products in good to high yields with a hig