145301-27-5Relevant articles and documents
Anellated pyridine compounds from hydrocodone and oxycodone, II: Diepoxy-bis-(iminoethano)-dinaphth[2,1-b:1',2'-i]acridines
Gorlitzer,Noack
, p. 637 - 641 (2007/10/02)
Michael addition of hydrocodone (1a) or oxycodone (1b) with their 7-benzylidene compounds 2 yields the enol half ketales 3. The 1,4-dihydropyridines 4 are obtained by heating 3 with ammonium acetate in acetic acid. 4d is prepared from 1b and 2b with ammon