145372-33-4 Usage
Description
2,3,3a,6,7,7a-Hexahydro-2S,7a-diMethyl-4-hydroxy-indene-1R-(1'-iodo)ethane 4-O-TrifluoroMethylsulfonate is a complex organic compound characterized by its unique molecular structure. It is a light yellow oil, which indicates its non-crystalline and liquid nature at room temperature. 2,3,3a,6,7,7a-Hexahydro-2S,7a-diMethyl-4-hydroxy-indene-1R-(1'-iodo)ethane 4-O-TrifluoroMethylsulfonate serves as an intermediate in the preparation of Dihydroxyvitamin D3 and its associated metabolites, which are essential for various biological functions, including calcium and phosphorus homeostasis and bone health.
Uses
Used in Pharmaceutical Industry:
2,3,3a,6,7,7a-Hexahydro-2S,7a-diMethyl-4-hydroxy-indene-1R-(1'-iodo)ethane 4-O-TrifluoroMethylsulfonate is used as an intermediate in the synthesis of Dihydroxyvitamin D3 for the pharmaceutical industry. Its role in the production of these essential vitamins is crucial, as they play a significant role in maintaining overall health and well-being.
Used in Research and Development:
In the field of research and development, this compound is used as a key intermediate for the synthesis of various metabolites related to Dihydroxyvitamin D3. This allows scientists to study the structure-activity relationships and explore potential therapeutic applications of these metabolites in treating various health conditions.
Used in Chemical Synthesis:
2,3,3a,6,7,7a-Hexahydro-2S,7a-diMethyl-4-hydroxy-indene-1R-(1'-iodo)ethane 4-O-TrifluoroMethylsulfonate is also utilized in chemical synthesis for the development of new compounds with potential applications in various industries, such as agriculture, materials science, and environmental science. Its unique structure and reactivity make it a valuable building block for creating novel molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 145372-33-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,3,7 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 145372-33:
(8*1)+(7*4)+(6*5)+(5*3)+(4*7)+(3*2)+(2*3)+(1*3)=124
124 % 10 = 4
So 145372-33-4 is a valid CAS Registry Number.
145372-33-4Relevant articles and documents
Ultrasonically Induced Conjugate Addition of Iodides to Electron-Deficient Olefins and Its Application to the Synthesis of Side-Chain Analogs of the Hormone 1α,25-Dihydroxyvitamin D3
Sestelo, Jose Perez,Mascarenas, Jose L.,Castedo, Luis,Murino, Antonio
, p. 118 - 123 (1993)
A versatile method for the rapid construction of fragments related to the upper part of vitamin D3 from the Lythgoe-Inhoffen diol is described.The key feature of the strategy is a new zinc-copper-induced conjugate addition of iodo triflate 10a to electron-deficient olefins under sonochemical aqueous conditions.These fragments are rapidly and efficiently transformed via the dienyne convergent approach to several derivatives of the hormone 1α,25-(OH)2-D3 modified at C-25.
