14545-01-8

Basic information

• Product Name: 1-(2,4-dinitrophenyl)imidazole
• Synonyms: 1-(2,4-dinitrophenyl)imidazole;1-(2,4-Dinitro-phenyl)-1H-imidazole
• CAS NO: 14545-01-8
• Molecular Formula: C₉H₆N₄O₄
• Molecular Weight: 234.17
• Mol File: 14545-01-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 441.6°C at 760 mmHg
• Flash Point: 220.9°C
• Appearance: /
• Density: 1.59g/cm³
• Vapor Pressure: 1.39E-07mmHg at 25°C
• Refractive Index: 1.708
• CAS DataBase Reference: 1-(2,4-dinitrophenyl)imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dinitrophenyl)imidazole(14545-01-8)
• EPA Substance Registry System: 1-(2,4-dinitrophenyl)imidazole(14545-01-8)

Safety Data

• Hazardous Substances Data: 14545-01-8(Hazardous Substances Data)

Usage

Description

1-(2,4-dinitrophenyl)imidazole, with the molecular formula C9H6N4O4, is a yellow crystalline powder that serves as a versatile reagent in organic and analytical chemistry. It is recognized for its ability to react with a wide range of nucleophiles, making it a valuable component in the synthesis of organic compounds and pharmaceuticals. Furthermore, its potential antimicrobial and anti-inflammatory properties have attracted attention in pharmaceutical research. However, due to its potential hazards to health and the environment, it is crucial to handle this compound with care.

Uses

Used in Organic and Analytical Chemistry:
1-(2,4-dinitrophenyl)imidazole is used as a reagent for its ability to react with various nucleophiles, facilitating the synthesis of a broad spectrum of organic compounds and pharmaceuticals.
Used in Chromogenic Detection:
1-(2,4-dinitrophenyl)imidazole is used as a chromogenic reagent for the detection of amino acids and peptides in biological samples, providing a means to identify and analyze these biomolecules.
Used in Pharmaceutical Research:
1-(2,4-dinitrophenyl)imidazole is used as a subject of interest in pharmaceutical research due to its potential antimicrobial and anti-inflammatory properties, which could lead to the development of new therapeutic agents.
Used in Synthesis of Organic Compounds and Pharmaceuticals:
1-(2,4-dinitrophenyl)imidazole is used as a key component in the synthesis of various organic compounds and pharmaceuticals, contributing to the development of new drugs and treatments.

InChI:InChI=1/C9H6N4O4/c14-12(15)7-1-2-8(9(5-7)13(16)17)11-4-3-10-6-11/h1-6H

Upstream product

• 288-32-4 1H-imidazole 
• 610-31-1 1,2,4-trinitrobenzene 
• 584-48-5 2,4-dinitrobromobenzene 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 70-34-8 2,4-Dinitrofluorobenzene 

Downstream Products

• 55033-69-7 Benzyl-N--N-formyl-carbamat 
• 1401032-88-9 1-(2,4-dinitrophenyl)-3-methylimidazolium triflate 
• 288-32-4 1H-imidazole 
• 51-28-5 2,4-Dinitrophenol 
• 13059-86-4 2,4-dinitro-N-butylaniline 
• 839-93-0 1-(2,4-dinitrophenyl)piperidine 

Relevant articles and documents

Coordination compound containing 1,10-phenanthroline-shaped N-heterocyclic carbene copper (I), and application thereof

The invention discloses a coordination compound containing 1,10-phenanthroline-shaped N-heterocyclic carbene copper (I) (as well as a coordinate compound monocrystal), and application thereof. The coordination compound containing the 1,10-phenanthroline-s

Direct N-arylation of azaheterocycles with aryl halides under ligand-free condition

A simple and efficient Ci￡N cross-coupling method of aryl halides with various heterocycles was reported, by using 10 mol% of CuI as catalyst and 1.2 equiv. NaH as base. Aryl iodides, aryl bromides and many substituted aryl chlorides could efficiently react with heterocycles, providing variety of N-arylated products in good to excellent yields. The ligand-free catalyst system was stable in air and could be readily reused. An efficient, convenient and applicable method was developed for the N-arylation of azaheterocycles catalyzed by CuI and NaH under ligand free condition. Copyright

REACTIVITY OF NUCLEOPHILES IN DIMETHYL SULFOXIDE AND ITS COMPARISON WITH NUCLEOPHILIC REACTIVITY IN PROTIC MEDIUM

Reactions of 2,4-dinitrophenyl acetate and 2,4-dinitrofluorobenzene as model substrates with 12 nucleophiles have been studied in dimethyl sulfoxide.The rate constants obtained have been discussed with regard to the nucleophilic reactivity differences in dimethyl sulfoxide and protic solvents inclusive of the different manifestations of the charge of nucleophiles.The applicability of an earlier-suggested correlation equation to the data obtained has been verified.The reaction medium markedly affects the reactivity of nucleophiles, the effect of charge being substantially greater in aprotic solvents (electrostatic interaction) than in protic ones (solvation).In spite of these differences the correlation with application of an empirical nucleophilicity scale suggested earlier is satisfactory, the regression coefficients obtained reflect changes in the nature of medium.