1459775-46-2

Basic information

• Product Name: 3-(3,4-dimethylphenyl)quinolin-2(1H)-one
• Synonyms: 3-(3,4-dimethylphenyl)quinolin-2(1H)-one
• CAS NO: 1459775-46-2
• Molecular Weight: 249.312
• Mol File: 1459775-46-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(3,4-dimethylphenyl)quinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-dimethylphenyl)quinolin-2(1H)-one(1459775-46-2)
• EPA Substance Registry System: 3-(3,4-dimethylphenyl)quinolin-2(1H)-one(1459775-46-2)

Safety Data

• Hazardous Substances Data: 1459775-46-2(Hazardous Substances Data)

Upstream product

• 95-20-5 2-methyl-1H-indole 
• 858467-52-4 1,2-dimethyl-4-(2-nitrovinyl)benzene 
• 948-65-2 2-phenyl-indole 
• 102-46-5 4-(chloromethyl)-1,2-dimethylbenzene 
• 552-89-6 2-nitro-benzaldehyde 
• 1225-93-0 2-phenyl-3-(2-nitrovinyl)-1H-indole 
• 95-47-6 o-xylene 
• 854179-33-2 1-(3,4-dimethylphenyl)-2-nitroethan-1-ol 
• 5973-71-7 3,4-dimethylbenzaldehyde 

Relevant articles and documents

Palladium-catalyzed carbonylative synthesis of 3-arylquinolin-2(1H)-ones from benzyl chlorides and o-nitrobenzaldehydes

A palladium-catalyzed carbonylative cyclization of benzyl chlorides with o-nitrobenzaldehydes has been developed for the synthesis of 3-arylquinolin-2(1H)-ones. Mo(CO)6 played a dual role as both a CO surrogate and a reductant in this carbonylative transformation.

Metal-free transannulation reaction of indoles with nitrostyrenes: A simple practical synthesis of 3-substituted 2-quinolones

3-Substituted 2-quinolones are obtained via a novel, metal-free transannulation reaction of 2-substituted indoles with 2-nitroalkenes in polyphosphoric acid. The reaction can be used in conjunction with the Fisher indole synthesis offering a practical three-component heteroannulation methodology to produce 2-quinolones from arylhydrazines, 2-nitroalkenes and acetophenone.