1470-39-9

Basic information

• Product Name: 2-(2-methoxyphenyl)-1H-indene-1,3(2H)-dione
• Synonyms: 2-(2-methoxyphenyl)-1H-indene-1,3(2H)-dione
• CAS NO: 1470-39-9
• Molecular Weight: 252.269
• Mol File: 1470-39-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-(2-methoxyphenyl)-1H-indene-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methoxyphenyl)-1H-indene-1,3(2H)-dione(1470-39-9)
• EPA Substance Registry System: 2-(2-methoxyphenyl)-1H-indene-1,3(2H)-dione(1470-39-9)

Safety Data

• Hazardous Substances Data: 1470-39-9(Hazardous Substances Data)

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 529-28-2 4-iodoanisol 
• 85-44-9 phthalic anhydride 
• 93-25-4 2-methoxyphenylacetic acid 
• 87-41-2 2-benzofuran-1(3H)-one 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 1435929-02-4 2-bromo-2-(2-methoxyphenyl)indan-1,3-dione 
• 104079-40-5 2-(2,2-Bis-ethylsulfanyl-ethyl)-2-(2-methoxy-phenyl)-indan-1,3-dione 
• 104079-38-1 [2-(2-Methoxy-phenyl)-1,3-dioxo-indan-2-yl]-acetaldehyde 
• 19055-49-3 2-(2'-Hydroxyphenyl)-1,3-indandion 
• 104079-36-9 2-Allyl-2-(2-methoxy-phenyl)-indan-1,3-dione 

Relevant articles and documents

Palladium-Catalyzed Direct α-Arylation of Indane-1,3-dione to 2-Substituted Indene-1,3-diones

A straightforward and feasible palladium-catalyzed direct α-arylation of indane-1,3-dione to 2-substituted aryl/heteroaryl indene-1,3-diones has been disclosed for the first time. Optimization of reaction conditions identified tBu-XPhos as a preferred ligand for the bis(acetonitrile)dichloropalladium(II) catalyst. A broad spectrum of aryl iodides and aryl triflates containing electron-donating, electron-withdrawing, and sterically hindered substituents gave an excellent yield for the quick access α-arylated 1,3-diones library.

Convenient and efficient synthesis of novel 11: H -benzo[5,6][1,4]thiazino[3,4- a] isoindol-11-ones derived from 2-bromo-(2/3-substitutedphenyl)-1 H -indene-1,3(2 H)-diones

An unprecedented formation of 11H-benzo[5,6][1,4]thiazino[3,4-a]isoindol-11-ones through a one-step reaction of differently substituted 2-aminobenzenethiols and 2-bromo-(2/3-substitutedphenyl)-1H-indene-1,3(2H)-diones in freshly dried ethanol under reflux conditions has been investigated. This unique transformation probably occurs through an initial nucleophilic substitution followed by ring opening and subsequent intramolecular cyclization. The structures of all the synthesized benzo[1,4]thiazino isoindolinones were established by FTIR, 1H NMR, 13C NMR, HRMS, and X-ray crystallographic analysis. This approach was found to be simple and convenient and provides several advantages such as substantial atom economy, short reaction time and operational simplicity.

INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS

The invention relates to indanone/indandione derivatives and heterocyclic analogs of Formula (I) wherein Ar1, A, B, L1, Y, Z, and (R1)n n are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments, especially as NPS receptor antagonists.