14796-89-5Relevant articles and documents
Substrate-Selective Olefin Hydrogenation with a Cavitand-Based Bis(N-anisyl iminophosphorane)
Chavagnan, Thierry,Bauder, Claude,Sémeril, David,Matt, Dominique,Toupet, Lo?c
, p. 70 - 76 (2017)
A distally-substituted resorcin[4]arene cavitand equipped with two remote N-anisyl-imino-phosphoranyl (AIP) units has been synthesised and assessed in the competitive hydrogenation of α-olefins (rhodium catalyst). A substrate-selectivity factor of 39.2 in
Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells
Meguro, Tomohiro,Terashima, Norikazu,Ito, Harumi,Koike, Yuka,Kii, Isao,Yoshida, Suguru,Hosoya, Takamitsu
supporting information, p. 7904 - 7907 (2018/07/25)
Efficient formation of water- and air-stable aza-ylides has been achieved using the Staudinger reaction between electron-deficient aromatic azides such as 2,6-dichlorophenyl azide and triarylphosphines. The reaction proceeds rapidly and has been successfully applied to chemical modification of proteins in living cells.
Synthesis of 4-fluoromethylsydnones and their participation in alkyne cycloaddition reactions
Foster, Robert S.,Adams, Harry,Jakobi, Harald,Harrity, Joseph P. A.
, p. 4049 - 4064 (2013/06/05)
We report the synthesis and some structural studies of 4-trifluoromethyl, 4-difluoromethyl-, and 4-monofluoromethylsydnones. All but the latter compounds are stable and represent effective precursors to a range of pyrazoles after cycloaddition reactions with alkynes. The cycloadditions are generally highly regioselective and provide 5-fluoromethylpyrazole products, although we have observed that Bn-substituted sydnones can provide an unexpected alkyne insertion mode that generates the 3-fluoromethyl isomer.