15266-35-0

Basic information

• Product Name: 1-Methyl-2-tridecylquinolin-4(1H)-one
• Synonyms: 1-Methyl-2-tridecylquinolin-4(1H)-one;Dihydroevocarpine;1-Methyl-2-tridecyl-4(1H)-quinolone
• CAS NO: 15266-35-0
• Molecular Formula: C23H35NO
• Molecular Weight: 341.5301
• Mol File: 15266-35-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 68-69℃
• Boiling Point: 447.0±45.0 °C(Predicted)
• Appearance: /
• Density: 0.964±0.06 g/cm3(Predicted)
• PKA: 2.52±0.70(Predicted)
• CAS DataBase Reference: 1-Methyl-2-tridecylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2-tridecylquinolin-4(1H)-one(15266-35-0)
• EPA Substance Registry System: 1-Methyl-2-tridecylquinolin-4(1H)-one(15266-35-0)

Safety Data

• Hazardous Substances Data: 15266-35-0(Hazardous Substances Data)

Usage

General Description

1-Methyl-2-tridecylquinolin-4(1H)-one, also known as T-61, is a synthetic chemical compound used as an avicide and a rodenticide. It is commonly used to control populations of pest birds and rodents in agricultural and urban settings. T-61 works by inhibiting the production of blood clotting factors in birds and mammals, leading to fatal internal bleeding. It is widely used due to its effectiveness in controlling pest populations, but concerns have been raised about its potential impact on non-target species and the environment. T-61 is typically applied as a bait or a liquid concentrate and is subject to regulations and restrictions in many countries due to its potential hazards.

Upstream product

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Relevant articles and documents

Quinolone alkaloids from Evodia rutaecarpa

Five new quinolone alkaloids were isolated from the fruits of Evodia rutaecarpa, together with seven known ones. Their structures were determined on the basis of spectral data and chemical reactions.

Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl- 4(1H)-quinolones

A series of 23 new 1-methyl-2-alkenyl-4(1H)quinolones have been synthesized and evaluated in vitro for their antimycobacterial activities against fast growing species of mycobacteria, such as Mycobacterium fortuitum, M. smegmatis and M. phlei. The compounds displayed good to excellent inhibition of the growth of the mycobacterial test strains with improved antimycobacterial activity compared to the hit compound, evocarpine. The most active compounds, which possessed chain length of 11-13 carbons at position-2 displayed potent inhibitory effects with an MIC value of 1.0 mg/L. In a human diploid embryonic lung cell line, MRC-5 cytotoxicity assay, the alkaloids showed weak to moderate cytotoxic activity. Biological evaluation of these evocarpine analogues on the less pathogenic fast growing strains of mycobacteria showed an interesting antimycobacterial profile and provided significant insight into the structure-activity relationships.

Evocarpin, a new alkaloid from Evodia rutaecarpa

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