153880-74-1

Basic information

• Product Name: 2,6-dimethylphenyl fluoroformate
• Synonyms: 2,6-dimethylphenyl fluoroformate
• CAS NO: 153880-74-1
• Molecular Weight: 168.168
• Mol File: 153880-74-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,6-dimethylphenyl fluoroformate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethylphenyl fluoroformate(153880-74-1)
• EPA Substance Registry System: 2,6-dimethylphenyl fluoroformate(153880-74-1)

Safety Data

• Hazardous Substances Data: 153880-74-1(Hazardous Substances Data)

Upstream product

• 876-99-3 2,6-dimethylphenyl chloroformic acid ester 

Downstream Products

• 443-88-9 2-fluoro-m-xylene 

Relevant articles and documents

Liquid-Phase Decarboxylation of Aromatic Haloformates: A New Access to Chloro- and Fluoroaromatics

The treatment of phenyl chloroformates 1 with a Lewis acid in the liquid phase resulted in decarboxylation to the corresponding chloroaromatics 2. Fluoroaromatic compounds were synthesized from phenylchloroformates 1 through a sequential fluorination/decarboxylation in the liquid phase by treatment with excess anhydrous hydrogen fluoride under mild conditions. In all cases, yields were increased by performing the reaction in 1,2,4-trichlorobenzene, which is inert to Friedel-Crafts reactions.

Process for the preparation of halogenated aromatics

Halogenated aromatics are prepared by heating halogenoformic acid esters to 80° to 280° C. in the presence of hydrogen fluoride or a catalytic amount of one or more Lewis acids from the group comprising aluminium halides, iron halides and antimony halides, and in the liquid phase.