154632-86-7

Basic information

• Product Name: O₁-benzyl-O₂-methyl-(2R)-aziridine-1,2-dicarboxylate
• Synonyms: O₁-benzyl-O₂-methyl-(2R)-aziridine-1,2-dicarboxylate
• CAS NO: 154632-86-7
• Molecular Weight: 235.24
• Mol File: 154632-86-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: O₁-benzyl-O₂-methyl-(2R)-aziridine-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: O₁-benzyl-O₂-methyl-(2R)-aziridine-1,2-dicarboxylate(154632-86-7)
• EPA Substance Registry System: O₁-benzyl-O₂-methyl-(2R)-aziridine-1,2-dicarboxylate(154632-86-7)

Safety Data

• Hazardous Substances Data: 154632-86-7(Hazardous Substances Data)

Upstream product

• 103539-32-8 (2R)-aziridine-2-carboxylic acid methyl ester 
• 501-53-1 benzyl chloroformate 
• 160233-42-1 (2R)-1-tritylaziridine-2-carboxylic acid methyl ester 
• 67-56-1 methanol 
• 1103830-29-0 (R)-1-[{(1'-Benzyloxycarbonyl)aziridin-2'-yl}carbonyl]-3,5-dimethyl-1H-pyrazole 

Downstream Products

• 1017575-35-7 methyl N-benzyloxycarbonyl-O-(2-((tert-butoxycarbonyl)(4-methoxybenzyl)amino)ethyl)-D-serinate 
• 209804-17-1 (R)-2-Benzyloxycarbonylamino-3-methoxy-propionic acid methyl ester 
• 103539-32-8 (2R)-aziridine-2-carboxylic acid methyl ester 
• 93204-37-6 (2R)-2-(benzyloxycarbonylamino)-3-tert-butoxypropionic acid methyl ester 
• 161253-78-7 (S)-2-{(R)-2-[((S)-1-{(R)-2-[(R)-2-Benzyloxycarbonylamino-3-(2-methyl-1H-indol-3-yl)-propionylamino]-3-methoxycarbonyl-propionyl}-pyrrolidine-2-carbonyl)-amino]-2-cyclopentyl-acetylamino}-4-methyl-pentanoic acid benzyl ester 
• 161253-87-8 (R)-2-Benzyloxycarbonylamino-3-(2-methyl-1H-indol-3-yl)-propionic acid 
• 783368-22-9 methyl N-[(benzyloxy)carbonyl]-O-{(1S)-2-[(tert-butoxycarbonyl)(cyclopropylmethyl)amino]-1-phenylethyl}-D-serinate 
• 21149-17-7 methyl 2-(benzyloxycarbonylamino)acrylate 
• 161253-88-9 (R)-2-Benzyloxycarbonylamino-3-(2-methyl-1H-indol-3-yl)-propionic acid methyl ester 

Relevant articles and documents

Aryl substituted aminotetrahydropyran compound and use thereof

The invention relates to an aryl substituted aminotetrahydropyran compound and use thereof, and further relates to a pharmaceutical composition comprising the compound. The compound or pharmaceuticalcomposition provided by the invention can be used as a dipeptidyl peptidase-IV (DPP-IV) inhibitor.

Catalytic aziridination of electron-deficient olefins with an N-chloro-N-sodio carbamate and application of this novel method to asymmetric synthesis

A new method for the aziridination of electron-deficient olefins using an N-chloro-N-sodio carbamate is described; the reaction was promoted by phase-transfer catalysis (solid-liquid) and afforded aziridines from α,β-unsaturated ketones, esters, sulfones and amides. The Royal Society of Chemistry 2008.

Efficient synthesis of (6R)-6-amino-1-methyl-4-(3-methylbenzyl)-hexahydro-1H-1,4-diazepine from methyl (2R)- and (2S)-1-benzyloxycarbonylaziridine-2-carboxylates

An efficient and practical method for the synthesis of (6R)-6-amino-1-methyl-4-(3-methylbenzyl)hexahydro-1H-1,4-diazepine 2, which serves as the amine part of DAT-582, a potent and selective 5-HT3 receptor antagonist, is described. The key inte