154822-66-9

Basic information

• Product Name: Isoxazole, 4-(4-methoxyphenyl)-3,5-dimethyl-
• CAS NO: 154822-66-9
• Molecular Formula: C12H13NO2
• Molecular Weight: 203.241
• Mol File: 154822-66-9.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Isoxazole, 4-(4-methoxyphenyl)-3,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazole, 4-(4-methoxyphenyl)-3,5-dimethyl-(154822-66-9)
• EPA Substance Registry System: Isoxazole, 4-(4-methoxyphenyl)-3,5-dimethyl-(154822-66-9)

Safety Data

• Hazardous Substances Data: 154822-66-9(Hazardous Substances Data)

Upstream product

• 79-24-3 Nitroethane 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 10558-25-5 4-bromo-3,5-dimethyl-1,2-oxazole 
• 10557-85-4 4-iodo-3,5-dimethylisoxazole 
• 171364-79-7 2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 5720-07-0 4-methoxyphenylboronic acid 
• 1160169-22-1 (Z)-4-amino-3-(4-methoxyphenyl)pent-3-en-2-one 
• 72969-10-9 3-(4'-methoxyphenyl)-pentane-2,4-dione 
• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 1160169-36-7 1-(2-(4-methoxyphenyl)-3-methyl-2H-azirin-2-yl)ethanone 
• 105-13-5 4-Methoxybenzyl alcohol 

Downstream Products

• 1355554-13-0 N-cyclopentyl-5-(3,5-dimethylisoxazol-4-yl)-2-hydroxybenzenesulfonamide 
• 1355554-31-2 N-cyclopentyl-5-(3,5-dimethylisoxazol-4-yl)-2-methoxybenzenesulfonamide 
• 1227693-30-2 5-(3,5-dimethylisoxazol-4-yl)-2-methoxybenzene-1-sulfonyl chloride 
• 1355770-63-6 (rac)-5-(3,5-dimethylisoxazol-4-yl)-2-methoxy-N-(piperidin-3-yl) benzenesulfonamide hydrochloride 
• 1355555-63-3 5-(3,5-dimethylisoxazol-4-yl)-2-methoxy-N-(piperidin-4-yl)benzenesulfonamide hydrochloride 
• 1355770-59-0 4-(4-methoxy-3-(piperazin-1-ylsulfonyl)phenyl)-3,5-dimethylisoxazole 
• 132572-89-5 3-(4-Methoxyphenyl)pentane-2,4-dione 

Relevant articles and documents

Simple Synthesis of Symmetrical 4-Substituted 3,5-Dialkylisoxazoles

A number of symmetrical 4-substituted 3,5-dialkylrsoxazoles have been prepared by treatment of aromatic aldehydes with nitroalkanes and aqueous sodium hydroxide.

The direct C(sp2)-H functionalization and coupling of aromatic N-heterocycles with (hetero)aryl bromides by [PdX2(imidazolidin-2-ylidene)(Py)] catalysts

In this study, a series of air- and moisture-stable imidazolidin-2-ylidene-based new palladium complexes with the general formula [PdX2(NHC)(Py)] were synthesized (NHC = N-heterocyclic carbene, Py = pyridine, X = Cl or I). The structures of the

Ferrocenyl palladacycles derived from unsymmetrical pincer-type ligands: Evidence of Pd(0) nanoparticle generation during the Suzuki-Miyaura reaction and applications in the direct arylation of thiazoles and isoxazoles

A new family of ferrocenyl-palladacycle complexes Pd(L1)Cl (Pd1) and Pd(L2)Cl (Pd2) were synthesized and characterized by UV-visible, IR, ESI-MS, and NMR spectral studies. The molecular structures of Pd1 and Pd2 were determined by X-ray crystallographic studies. Palladacycle catalyzed Suzuki-Miyaura cross-coupling reactions were investigated utilizing the derivatives of phenylboronic acids and substituted chlorobenzenes. Mechanistic investigation authenticated the generation of Pd(0) nanoparticles during the catalytic cycle and the nanoparticles were characterized by XPS, SEM and TEM analysis. Direct C-H arylation of thiazole and isoxazole derivatives employing these ferrocenyl-palladacycle complexes was examined. The reaction model for the arylation reaction implicating the in situ generation of Pd(0) nanoparticles was proposed.