156276-25-4

Basic information

• Product Name: DL-LEUCIC ACID ISOPROPYL ESTER
• Synonyms: DL-2-HYDROXYISOCAPROIC ACID ISOPROPYL ESTER;DL-LEUCIC ACID ISOPROPYL ESTER;ISOPROPYL DL-2-HYDROXY-4-METHYLVALERATE;ISOPROPYL DL-LEUCATE;Isopropyl DL-2-Hydroxy-4-methylvalerate DL-Leucic Acid Isopropyl Ester;Isopropyl 2-hydroxy-4-methylpentanoate
• CAS NO: 156276-25-4
• Molecular Formula: C9H18O3
• Molecular Weight: 174.24
• Mol File: 156276-25-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 206.3oC at 760 mmHg
• Flash Point: 77oC
• Appearance: /
• Density: 0,94 g/cm3
• Vapor Pressure: 0.0564mmHg at 25°C
• Refractive Index: 1.4200 to 1.4240
• CAS DataBase Reference: DL-LEUCIC ACID ISOPROPYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: DL-LEUCIC ACID ISOPROPYL ESTER(156276-25-4)
• EPA Substance Registry System: DL-LEUCIC ACID ISOPROPYL ESTER(156276-25-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 156276-25-4(Hazardous Substances Data)

Usage

General Description

DL-Leucic acid isopropyl ester is a chemical compound that is commonly used in the field of organic synthesis and pharmaceuticals. It is an ester of DL-Leucic acid, which is a naturally occurring amino acid that plays a crucial role in protein synthesis and cellular metabolism. The isopropyl ester form of DL-Leucic acid isopropyl ester makes it more stable and suitable for various applications. DL-LEUCIC ACID ISOPROPYL ESTER is also known for its potential as an anti-catabolic agent, which means it may help prevent muscle breakdown and promote muscle growth. It is used as a dietary supplement and is being researched for its potential benefits in sports performance and muscle health. Additionally, DL-Leucic acid isopropyl ester may have potential applications in the development of pharmaceutical drugs and other biotechnological products.

InChI:InChI=1/C9H18O3/c1-6(2)5-8(10)9(11)12-7(3)4/h6-8,10H,5H2,1-4H3

Upstream product

• 25006-60-4 isopropyl dichloroacetate 
• 21806-22-4 2-chloro-3-isopropyl-oxiranecarboxylic acid isopropyl ester 
• 10303-64-7 2-hydroxy-4-methylpentanoic acid 
• 67-63-0 isopropyl alcohol 

Relevant articles and documents

Determination of the absolute configuration of the fragments composing the phytotoxin phomalide

The absolute configurations of the residues constituting phomalide (1) were determined on the products resulting from acidic hydrolysis. The configurations of the amino acids Val and Leu were determined as (S) and (R), respectively, by chiral GC analysis (Chirasil-Val capillary column), employing N-trifluoroacetyl (TFA) amino acid methyl ester derivatives. The configurations of the hydroxy acids O-Phe and O-Leu were determined as (S) by 1H NMR of the Mosher's esters of the isopropyl ester derivatives. The method described allowed for the unambiguous assignment of the absolute configuration of the α-amino and α-hydroxy acid residues composing phomalide (1). The absolute configurations of the residues constituting phomalide (1) were determined on the products resulting from acidic hydrolysis. The configurations of the amino acids Val and Leu were determined as (S) and (R), respectively, by chiral GC analysis (Chirasil-Val capillary column), employing N-trifluoroacetyl (TFA) amino acid methyl ester derivatives. The configurations of the hydroxy acids O-Phe and O-Leu were determined as (S) by 1H NMR of the Mosher's esters of the isopropyl ester derivatives. The method described allowed for the unambiguous assignment of the absolute configuration of the α-amino and α-hydroxy acid residues composing phomalide (1).

New efficient synthesis of α-hydroxyesters from carbonyl compounds via α-chloroglycidic esters

The chain extension with an α-hydroxyester unit of various carbonyl compounds was realized, in two steps, via α-chloroglycidic esters. Synthesis, results and expected mechanisms are reported. (C) 2000 Published by Elsevier Science Ltd.