157364-93-7

Basic information

• Product Name: 2'-hydroxy-1,1'-binaphthalen-2-yl benzoylformate
• Synonyms: 2'-hydroxy-1,1'-binaphthalen-2-yl benzoylformate
• CAS NO: 157364-93-7
• Molecular Weight: 418.449
• Mol File: 157364-93-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-hydroxy-1,1'-binaphthalen-2-yl benzoylformate(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-hydroxy-1,1'-binaphthalen-2-yl benzoylformate(157364-93-7)
• EPA Substance Registry System: 2'-hydroxy-1,1'-binaphthalen-2-yl benzoylformate(157364-93-7)

Safety Data

• Hazardous Substances Data: 157364-93-7(Hazardous Substances Data)

Upstream product

• 602-09-5 (-)-2,2'-dihydroxy-1,1'-binaphthyl 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 3966-30-1 (R)-Atrolactic acid 
• 13113-71-8 (S)-Atrolactic acid 

Relevant articles and documents

Diastereoselectivity in addition of methylmagnesium halide to benzoylformate of chiral 1,1'-binaphthalene-2,2'-diol

The Grignard reactions of mono-benzoylformate ester of 1,1'-binaphthalene-2,2'-diol were examined to investigate the complex-induced proximity effect of the phenolic hydroxyl at C-2' under different reaction conditions. This hydroxyl group exerted a significant neighboring group participation in the reaction. The nucleophilic addition reaction proceeded with higher diastereoselectivity than that of a series of sterically similarly sized binaphthyl esters recently reported. The halogen ligand in methyl Grignard reagents plays a crucial role in controlling the degree and sense of diastereoselectivity. A plausible mechanism is also proposed.