157429-20-4

Basic information

• Product Name: C₁₀H₁₀FN₃OS
• Synonyms: C₁₀H₁₀FN₃OS
• CAS NO: 157429-20-4
• Molecular Weight: 239.273
• Mol File: 157429-20-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₀FN₃OS(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₀FN₃OS(157429-20-4)
• EPA Substance Registry System: C₁₀H₁₀FN₃OS(157429-20-4)

Safety Data

• Hazardous Substances Data: 157429-20-4(Hazardous Substances Data)

Upstream product

• 79784-37-5 (2-Fluoro-5-methyl-phenyl)-oxo-acetaldehyde 
• 79-19-6 thiosemicarbazide 
• 352-32-9 p-fluorotoluene 
• 446-07-1 1-(2-fluoro-5-methylphenyl)ethan-1-one 

Relevant articles and documents

FLUORINE CONTAINING BIOACTIVE HETEROCYCLES PART III : SYNTHESIS OF SOME NEW FLUORINE CONTAINING PHENYLGLYOXALS AND 1,2,4-TRIAZINE DERIVATIVES

Some medicinally important new fluorine containing phenylglyoxals have been synthesized by selenium dioxide oxidation of appropriate fluorinated acetophenones and characterized by spectrum studies.The phenylglyoxals were treated with thiosemicarbazide to give corresponding thiosemicarbazones (III) which were cyclized, in situ, to yield 5-(fluorophenyl)-1,2,4-triazine-3(2H)-thiones.The 5-(4-fluorophenyl)-1,2,4-triazine-3-(2H)-thione (IV) undergoes nucleophilic displacement when refluxed with hydrazine hydrate to give corresponding 3-hydrazino-5-(4-fluorophenyl)-1,2,4-tria zine.The hydrazino derivative reacts with fluorinated 1,3-diketones, in glacial acetic acid yielding 5-(4-fluorophenyl)-3--1,2,4-triazines (VII).All synthesized compounds have been characterized on the basis of elemental analyses, ir, pmr and 19F nmr studies.