1589590-44-2

Basic information

• Product Name: C₁₆H₂₄O₂
• Synonyms: C₁₆H₂₄O₂
• CAS NO: 1589590-44-2
• Molecular Weight: 248.365
• Mol File: 1589590-44-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₄O₂(1589590-44-2)
• EPA Substance Registry System: C₁₆H₂₄O₂(1589590-44-2)

Safety Data

• Hazardous Substances Data: 1589590-44-2(Hazardous Substances Data)

Upstream product

• 626-20-0 3-methoxystyrene 
• 93782-92-4 (E)-6-iodo-5-methylhex-5-en-1-ol 

Downstream Products

• 469-83-0 (+/-)-cafestol 
• 1424371-49-2 C₁₆H₂₂O₂ 

Relevant articles and documents

Total synthesis of (±)-cafestol: A late-stage construction of the furan ring inspired by a biosynthesis strategy

An efficient bioinspired approach to the total synthesis of (±)-cafestol features a late-stage installation of the furan ring with a mild Au-catalyzed cycloisomerization. The Et2AlCl-promoted aldehyde-ene cyclization and subsequent Friedel-Crafts reaction deliver a requisite tricyclic system in gram scale with high stereo- and regioselectivity. Moreover, a highly stereoselective SmI2-mediated aldehyde-alkene radical cyclization furnishes the key bicyclo[3.2.1]octane skeleton to offer an advanced intermediate for the synthesis of other oxygenated ent-kaurene diterpenoids.