1590368-21-0Relevant articles and documents
Organocatalytic synthesis of (Arylselanyl)phenyl-1H-1,2,3-triazole-4- carboxamides by cycloaddition between azidophenyl arylselenides and β-oxo-amides
Seus, Natalia,Goldani, Bruna,Lenardao, Eder J.,Savegnago, Lucielli,Paixao, Marcio W.,Alves, Diego
supporting information, p. 1059 - 1065 (2014/03/21)
We describe the use of β-oxo-amides in organocatalytic cycloaddition with aryl azidophenyl selenides. The cycloaddition reactions were performed under mild conditions, with β-oxo-amides and aryl azidophenyl selenides in the presence of a catalytic amount of Et2NH (5 mol-%), and the corresponding products were obtained in good to excellent yields. This organocatalytic methodology tolerated a range of substituents either in the β-oxo-amides or in the aryl azidophenyl selenides and proved to be an efficient methodology for the combinatorial synthesis of new selenium-containing triazole compounds. The use of β-oxo-amides in organocatalytic cycloaddition with aryl azidophenyl selenides has been developed, with the corresponding (arylselanyl)phenyl-1H-1,2,3-triazole-4-carboxamides being obtained in good to excellent yields. This organocatalytic protocol proved to be an efficient methodology for the combinatorial synthesis of new selenium-containing triazole compounds. Copyright
