159084-46-5

Basic information

• Product Name: 4-((5-phenyl-2H-tetrazol-2-yl)methyl)morpholine
• Synonyms: 4-((5-phenyl-2H-tetrazol-2-yl)methyl)morpholine
• CAS NO: 159084-46-5
• Molecular Weight: 245.284
• Mol File: 159084-46-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-((5-phenyl-2H-tetrazol-2-yl)methyl)morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((5-phenyl-2H-tetrazol-2-yl)methyl)morpholine(159084-46-5)
• EPA Substance Registry System: 4-((5-phenyl-2H-tetrazol-2-yl)methyl)morpholine(159084-46-5)

Safety Data

• Hazardous Substances Data: 159084-46-5(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 110-91-8 morpholine 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 18039-42-4 5-phenyl-2H-1,2,3,4-tetrazole 

Downstream Products

• 18039-42-4 5-phenyl-2H-1,2,3,4-tetrazole 
• 113137-82-9 4-(5-phenyltetrazole-2-yl)-2-butanone 

Relevant articles and documents

NMR study of the tautomeric behavior of N -(α-Aminoalkyl)tetrazoles

N-(α-Aminoalkyl)tetrazoles exist in solution as equilibrium mixtures of N1 and N2 tautomers. The position of equilibrium depends significantly on the polarity of the solvent and the substituents in the tetrazole ring. Interconversion between individual tautomers is shown to proceed via tight ion-pair intermediates in which intramolecular recombination is faster than the intermolecular crossover since the latter probably requires solvent separation of ion-pair intermediates.

AMINOMETHYLATION OF 5-SUBSTITUTED TETRAZOLES

The Mannich reaction of 5-substituted tetrazoles with formaldehyde and secondary amines was described.Some of the synthesized 2-(N,N-dialkyl-aminomethyl)-5-substituted tetrazoles on treatment with aliphatic ketones gave the corresponding 3-(5-substituted tetrazolyl-2)-1 ones in moderate yields.