1593111-61-5

Basic information

• Product Name: C₅₈H₈₀N₄O₁₉S
• Synonyms: C₅₈H₈₀N₄O₁₉S
• CAS NO: 1593111-61-5
• Molecular Weight: 1169.35
• Mol File: 1593111-61-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₅₈H₈₀N₄O₁₉S(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₈H₈₀N₄O₁₉S(1593111-61-5)
• EPA Substance Registry System: C₅₈H₈₀N₄O₁₉S(1593111-61-5)

Safety Data

• Hazardous Substances Data: 1593111-61-5(Hazardous Substances Data)

Upstream product

• 156153-43-4 4-(N,N-dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole 
• 145075-81-6 3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-{O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-(1->3)-2-O-acetyl-β-L-arabinopyranoside} 

Relevant articles and documents

Fluorescent analog of OSW-1 and its cellular localization

OSW-1 is a steroidal saponin, which has emerged as an attractive anticancer agent with highly cancer cell selective activity. A fluorescent analog was prepared from the natural product to analyze its cellular uptake and localization. We found that the fluorescent analog is rapidly internalized into cells and is primarily distributed in endoplasmic reticulum and Golgi apparatus.

Synthesis of OSW-1 derivatives by site-selective acylation and their biological evaluation

A strategy to site-selectively monoacylate an antitumor saponin OSW-1 was developed using an organotin reagent to rapidly access its derivatives that are useful as chemical probes. 4″-O-Acylated OSW-1 derivatives bearing a fluorophore, an alkyne tag, or biotin were prepared in good yields and were shown to maintain highly cytotoxic activity.