1599466-85-9 Usage
Description
RuPhos Palladacycle Gen. 4 is a highly effective and versatile catalyst used in various chemical reactions, particularly in cross-coupling reactions. It is a fourth-generation palladacycle, which is a type of organopalladium compound, and is known for its stability and solubility in most organic solvents.
Uses
Used in Chemical Synthesis:
RuPhos Palladacycle Gen. 4 is used as a powerful ligand for classic cross-coupling reactions, enhancing the efficiency and selectivity of these reactions. Its stability and solubility in various organic solvents make it a preferred choice for chemists working in the field of chemical synthesis.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, RuPhos Palladacycle Gen. 4 is used as a catalyst for the synthesis of complex organic molecules, which are often the active ingredients in various drugs. Its ability to facilitate cross-coupling reactions allows for the creation of new and innovative drug candidates with improved properties.
Used in Material Science:
In the field of material science, RuPhos Palladacycle Gen. 4 is used as a catalyst for the synthesis of advanced materials, such as polymers and nanoparticles, with specific properties tailored for various applications, including electronics, energy storage, and environmental remediation.
Used in Research and Development:
RuPhos Palladacycle Gen. 4 is also used in research and development laboratories, where it is employed to explore new reaction pathways and develop novel synthetic methods. Its versatility and stability make it an invaluable tool for chemists working on the cutting edge of chemical research.
Reactions
Catalyst for the Buchwald-Hartwig Cross-Coupling Reaction
Check Digit Verification of cas no
The CAS Registry Mumber 1599466-85-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,9,9,4,6 and 6 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1599466-85:
(9*1)+(8*5)+(7*9)+(6*9)+(5*4)+(4*6)+(3*6)+(2*8)+(1*5)=249
249 % 10 = 9
So 1599466-85-9 is a valid CAS Registry Number.
1599466-85-9Relevant articles and documents
N-substituted 2-aminobiphenylpalladium methanesulfonate precatalysts and their use in C-C and C-N cross-couplings
Bruno, Nicholas C.,Niljianskul, Nootaree,Buchwald, Stephen L.
, p. 4161 - 4166 (2014/05/20)
A series of phosphine-ligated palladium precatalysts based on N-methyl- and N-phenyl-2-aminobiphenyl have been developed. Substitution at the nitrogen center prevents the presence of traces of aminobiphenyls that contain a free -NH2 group from contaminating cross-coupling products. These precatalysts produce N-substituted carbazoles upon activation, which cannot consume starting materials. These precatalysts were efficiently generated from 2-aminobiphenyl with minimal purification and found to be highly effective in Suzuki-Miyaura and C-N cross-coupling reactions.