160721-28-8

Basic information

• Product Name: Acetic acid, [(3-hydroxyphenyl)methoxy]-, ethyl ester
• CAS NO: 160721-28-8
• Molecular Formula: C11H14O4
• Molecular Weight: 210.23
• Mol File: 160721-28-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetic acid, [(3-hydroxyphenyl)methoxy]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [(3-hydroxyphenyl)methoxy]-, ethyl ester(160721-28-8)
• EPA Substance Registry System: Acetic acid, [(3-hydroxyphenyl)methoxy]-, ethyl ester(160721-28-8)

Safety Data

• Hazardous Substances Data: 160721-28-8(Hazardous Substances Data)

Upstream product

• 620-24-6 3-Hydroxybenzyl alcohol 
• 191097-27-5 methanesulfonic acid 3-benzyloxybenzyl ester 
• 64-17-5 ethanol 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 100-39-0 benzyl bromide 
• 672931-11-2 ethyl {[3-(methoxymethoxy)benzyl]oxy}acetate 
• 160721-26-6 t-butyl 4-<3-(benzyloxy)phenyl>-3-oxabutanoate 
• 1700-30-7 (3-(benzyloxy)phenyl)methanol 
• 160721-27-7 ethyl 4-<3-(benzyloxy)phenyl>-3-oxabutanoate 

Downstream Products

• 143536-49-6 (3-Hydroxy-benzyloxy)-acetaldehyde 
• 143536-29-2 4,5-dihydroxy-benzo<2H>dihydropyran 

Relevant articles and documents

CYCLOHEXANE DERIVATIVE COMPOUND

To find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, the agent having excellent activity and high safety. A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents an optionally substituted phenylene group; B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-C10 aryl group, or an optionally substituted C3-C10 cycloalkyl group; R1 represents a hydrogen atom or a C1-C3 alkyl group; R2 represents a hydrogen atom or a C1-C3 alkyl group; R3 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group, a C1-C3 alkoxy C1-C3 alkyl group, or a C1-C3 hydroxyalkyl group; R4 represents a hydrogen atom, a C1-C6 alkyl group, or a halogen atom; n represents an integer of 1 to 4; and X represents methylene, -O-, -NH-, -N(C1-C3 alkyl)-, -C(=O)-, -S-, -S(O)-, -S(O2)- or a single bond.

Regioselective synthesis of 1,8-dihydroxytetralins through a tandem reduction/intramolecular hydroxyalkylation of 4-(3-hydroxyphenyl)alkanoates

A series of 4-(3-hydroxyphenyl)butanoates 3 has been prepared and transformed into 1,8-dihydroxytetralins of general formula 2 by treatment with 2 equivalents of DIBALH followed by quenching with aqueous NH4Cl. A possible mechanism for this novel totally regioselective intramolecular hydroxyalkylation is suggested and the factors affecting the stability of 1,8-dihydroxytetralins 2 are also discussed.