16096-86-9

Basic information

• Product Name: Benzenesulfinamide, 4-chloro-
• CAS NO: 16096-86-9
• Molecular Formula: C6H6ClNOS
• Molecular Weight: 175.639
• Mol File: 16096-86-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenesulfinamide, 4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfinamide, 4-chloro-(16096-86-9)
• EPA Substance Registry System: Benzenesulfinamide, 4-chloro-(16096-86-9)

Safety Data

• Hazardous Substances Data: 16096-86-9(Hazardous Substances Data)

Upstream product

• 106-54-7 p-Chlorothiophenol 
• 26760-21-4 methyl p-chlorobenzenesulphinate 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 21969-11-9 1-(4-chlorophenylthio)-4-nitrobenzene 
• 89244-07-5 C₁₂H₉ClN₂O₃S 
• 24535-53-3 4-nitro-4’-chlorodiphenylsulfoxide 

Downstream Products

• 847980-48-7 N-dihydrocinnamoyl-p-chlorobenzenesulfinamide 
• 14934-03-3 4-chloro-N-(4-chlorophenyl)benzenesulfinamide 
• 342401-19-8 N-((4-chlorophenyl)sulfinyl)benzamide 
• 731-17-9 N-Benzoyl-p-chlorbenzolsulfonimidoylchlorid 
• 1264737-72-5 N-[(4-chlorophenyl)-oxo-(trifluoromethyl)-λ6-sulfanylidene]benzamide 
• 1264737-60-1 N-benzoyl-4-chlorophenyl sulfonimidoyl fluoride 
• 847980-59-0 (S)-N-dihydrocinnamoyl-p-chlorobenzenesulfinamide 

Relevant articles and documents

2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 2-amino-N-(amino-oxo-aryl-λ6- sulfanylidene)acetamide compounds (referred to herein as ANASIA compounds) that, inter alia, inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase (aaRS) (e.g., bacterial leucyl-tRNA synthetase, LeuRS). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase; to treat disorders that are ameliorated by the inhibition (e.g., selective inhibition) of bacterial aminoacyl-tRNA synthetase; to treat bacterial infections; etc.

Synthesis of asymmetrical thioethers with sulfinamides as the sulfenylation agent under metal-free conditions

Using sulfinamides as a new reagent for preparation of asymmetrical thioethers has been developed under metal-free conditions. The reactions proceeded smoothly without the use of stinky thiophenol, highly toxic sulfonyl chloride or oxidant. Such a simple, efficient transformation provides an attractive approach to various diaryl sulfides in good to excellent yields.

CONVENIENT ONE-POT SYNTHESIS OF ARENESULFINAMIDES: REACTIONS OF 4-NITROPHENYL SUBSTITUTED PHENYL SULFOXIDES WITH ELEMENTAL SULFUR IN LIQUID AMMONIA

Various arenesulfinamides were synthesized in good yields by one-pot reactions of 4-nitrophenyl-substituted phenyl sulfoxides with elemental sulfur in liquid ammonia.The arenesulfinamides were further reduced with elemental sulfur in liquid ammonia to give corresponding disulfides.