1611-56-9

Basic information

• Product Name: 11-Bromo-1-undecanol
• Synonyms: 11-Bromo-1-hydroxyundecane;11-Bromoundecan-1-ol;1-Bromo-11-hydroxyundecane;UNDECAMETHYLENE BROMOHYDRIN;11-BROMOUNDECANOL;11-BROMOUNDECYL ALCOHOL;11-BROMO-1-UNDECANOL;11-BROMO-1-UNDECANOL CRYSTALLINE
• CAS NO: 1611-56-9
• Molecular Formula: C₁₁H₂₃BrO
• Molecular Weight: 251.2
• EINECS: 216-554-3
• Product Categories: omega-Bromoalkanols;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Linear hydrocarbon series;Alcohols;Building Blocks;C11 to C30+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;OLED materials,pharm chemical,electronic
• Mol File: 1611-56-9.mol
• Article Data: 21

Chemical Properties

• Melting Point: 46-49 °C(lit.)
• Boiling Point: 165-170 °C1 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: White to beige/Crystals or Crystalline Powder
• Density: 1.1887 (rough estimate)
• Vapor Pressure: 2.8E-06mmHg at 25°C
• Refractive Index: 1.5290 (estimate)
• Storage Temp.: 0-10°C
• Solubility: chloroform: soluble50mg/mL, clear to slightly hazy, colorless to
• PKA: 15.20±0.10(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 1741180
• CAS DataBase Reference: 11-Bromo-1-undecanol(CAS DataBase Reference)
• NIST Chemistry Reference: 11-Bromo-1-undecanol(1611-56-9)
• EPA Substance Registry System: 11-Bromo-1-undecanol(1611-56-9)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 3
• Hazardous Substances Data: 1611-56-9(Hazardous Substances Data)

Usage

Description

11-Bromo-1-undecanol is an organic compound with the chemical formula C11H23BrO. It is a white to beige crystalline powder or crystals, known for its unique chemical properties and versatile applications across various industries.

Uses

Used in Chemical Synthesis:
11-Bromo-1-undecanol is used as a key intermediate in the synthesis of various organic compounds. It serves as a starting material for the preparation of 11-mercapto-1-undecanol and 1-(2-acryloyloxyundecyl)-3-methylimidazolium bromide, which are essential in the development of new chemical products and materials.
Used in Polymer Industry:
In the polymer industry, 11-Bromo-1-undecanol is utilized as a monomer in the one-pot synthesis of graft copolymers. These copolymers are based on a metathesis skeleton with poly(methyl methacrylate) grafts, which are crucial for creating advanced polymer materials with improved properties and applications.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, 11-Bromo-1-undecanol, due to its chemical structure, could potentially be used in the pharmaceutical industry for the development of new drugs or drug delivery systems, given its compatibility with various chemical reactions and its ability to form different compounds.

InChI:InChI=1/C11H23BrO/c12-10-8-6-4-2-1-3-5-7-9-11-13/h13H,1-11H2

Upstream product

• 112-46-9 9-undecenol 
• 15949-84-5 11-bromoundecanoyl chloride 
• 112-19-6 10-undecenyl acetate 
• 6271-23-4 11-bromoundecanoic acid ethyl ester 
• 6287-90-7 11-bromo-undecanoic acid methyl ester 
• 2834-05-1 11-bromoundecanoic acid 
• 109-63-7 trifluoroborane diethyl ether 
• 70326-40-8 11-bromoundecan-1-al 
• 30295-23-9 11-bromoundecanyl acetate 
• 19779-06-7 sodium hexanolate 
• 4850-47-9 11-hydroxy-undecanenitrile 
• 53463-68-6 1-bromo-10-decanol 
• 13688-67-0 1,10-undecadiene 
• 101686-44-6 11-bromo-1-hydroxyundecane 

Downstream Products

• 19101-00-9 (11?hydroxyundecyl)triphenylphosphonium bromide 
• 144878-51-3 11-bromoundecan-1-yl benzyl ether 
• 148773-60-8 11-(phenylthio)-1-undecanol 
• 73780-20-8 ethyl 4-<(11-hydroxyundecyl)amino>benzoate 
• 135529-08-7 2-hydroxy-4-(11-hydroxyundecyloxy)benzaldehyde 
• 3732-23-8 Hydrochinon-bis-(11-hydroxy-undecyl-aether) 
• 179486-14-7 4-[4-(11-Hydroxy-undecyloxy)-phenylazo]-phenol 
• 443678-72-6 17-Hydroxy-6-thia-heptadecanoic acid 
• 603132-78-1 N-benzyl-N'-bromoundecyl-N'-tert-butoxycarbonyl sulfamide 
• 428515-75-7 11-[4-(4-butyl-phenylazo)-phenoxy]-undecan-1-ol 
• 585521-18-2 4-{(E)-2-[3,5-Bis-(11-bromo-undecyloxy)-phenyl]-vinyl}-benzoic acid methyl ester 
• 119438-02-7 11-hydroxyundecyldisulfide 
• 899439-62-4 11-2-[(11-hydroxyundecyl)oxy]-4,5-diiodophenoxy-1-undecanol 
• 463-36-5 11-fluoroundecan-1-ol 

Relevant articles and documents

Synthesis of Terminally Substituted 9-Alkylidene-10-methyl Acridans

ω-Substituted undecanals 1 and 2 reacted with acridine derivatives 3 and 5 to give the terminally substituted 9-alkylidene-10-methylacridans 6.The compounds prepared were highly fluorescent and exhibited chemiluminescent activity. - Keywords: Acridans; Chemiluminescence.

(Z,Z)-5,27-tritriacontadiene: Major sex pheromone of Drosophila pallidosa (Diptera; Drosophilidae)

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Design, synthesis and antiparasitic evaluation of click phospholipids

A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised miltefosine analogues. The compounds were evaluated for their in vitro antiparasitic activity against Leishmania infantum and Leishmania donovani intracellular amastigotes, against Trypanosoma brucei brucei and against different developmental stages of Trypanosoma cruzi. The nature of the substituents of the heterocyclic ring (tail) and the oligomethylene spacer between the head group and the heterocyclic ring was found to affect the activity and toxicity of these compounds leading to a significantly improved understanding of their structure–activity relationships. The early ADMET profile of the new derivatives did not reveal major liabilities for the potent compounds. The 1,2,3-triazole derivative 27 substituted by a decyl tail, an undecyl spacer and a choline head group exhibited broad spectrum antiparasitic activity. It possessed low micromolar activity against the intracellular amastigotes of two L. infantum strains and T. cruzi Y strain epimastigotes, intracellular amastigotes and trypomastigotes, while its cytotoxicity concentration (CC50) against THP-1 macrophages ranged between 50 and 100 μM. Altogether, our work paves the way for the development of improved ether phospholipid derivatives to control neglected tropical diseases.

Highly Chemoselective Deprotection of the 2,2,2-Trichloroethoxycarbonyl (Troc) Protecting Group

Nonreducing, pH-neutral conditions for the selective cleavage of the 2,2,2-trichloroethoxycarbonyl (Troc) protecting group are reported. Using trimethyltin hydroxide in 1,2-dichloroethane, Troc-protected alcohols, thiols, and amines can be selectively unmasked in the presence of various functionalities that are incompatible with the reducing conditions traditionally used to remove the Troc group. This mild deprotection protocol tolerates a variety of other hydrolytically sensitive and acid/base-sensitive moieties as well.