16232-04-5Relevant articles and documents
Synthesis of azachalcones, their α-amylase, α-glucosidase inhibitory activities, kinetics, and molecular docking studies
Saleem, Faiza,Kanwal,Khan, Khalid Mohammed,Chigurupati, Sridevi,Solangi, Mehwish,Nemala, Appala Raju,Mushtaq, Maria,Ul-Haq, Zaheer,Taha, Muhammad,Perveen, Shahnaz
, (2020/12/09)
Diabetes being a chronic metabolic disorder have attracted the attention of medicinal chemists and biologists. The introduction of new and potential drug candidates for the cure and treatment of diabetes has become a major concern due to its increased pre
Inhibitory potential of some chalcones on cathepsins B, H and L
Garg, Shweta,Raghav, Neera
, p. 72937 - 72949 (2015/09/15)
Cathepsins, intracellular proteases, are known to be involved in a number of physiological processes such as degradation of extracellular proteins, prohormone processing, progressions of atherosclerosis etc. High levels of cathepsins have also been indica
Efficient and Clean Aldol Condensation Catalyzed by Sodium Carbonate in Water
Zhang, Ze,Dong, Ya-Wei,Wang, Guan-Wu
, p. 966 - 967 (2007/10/03)
Efficient and environmentally friendly synthesis of chalcone and azachalcone was performed by aldol condensation of aldehydes with ketones in pure water catalyzed by sodium carbonate. In this convenient methodology, side reactions were avoided and thus high yields were achieved.