16308-68-2 Usage
Description
ALLYL PHENYL CARBONATE 97 is a chemical compound that can be synthesized by reacting phenyl chloroformate and allyl alcohol in the presence of pyridine. It is known for its ability to react with (2-alkynyl)phenylisocyanate, catalyzed by a P(0)/Cu(I) system, to produce the corresponding indole.
Uses
Used in Chemical Synthesis:
ALLYL PHENYL CARBONATE 97 is used as a reactant in the synthesis of various organic compounds. It is particularly useful in the production of indole derivatives through its reaction with (2-alkynyl)phenylisocyanate, catalyzed by a P(0)/Cu(I) system.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, ALLYL PHENYL CARBONATE 97 can be utilized as an intermediate in the synthesis of various drug molecules. Its ability to form indole derivatives makes it a valuable component in the development of potential therapeutic agents.
Used in Research and Development:
ALLYL PHENYL CARBONATE 97 is also used in research and development settings to explore its potential applications in various chemical reactions and to understand its properties and behavior in different reaction conditions. This knowledge can contribute to the advancement of chemical synthesis techniques and the discovery of new compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 16308-68-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,3,0 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16308-68:
(7*1)+(6*6)+(5*3)+(4*0)+(3*8)+(2*6)+(1*8)=102
102 % 10 = 2
So 16308-68-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H10O3/c1-2-8-12-10(11)13-9-6-4-3-5-7-9/h2-7H,1,8H2
16308-68-2Relevant articles and documents
A mild ligand-free iron-catalyzed liberation of alcohols from allylcarbonates
Dieskau, Andre P.,Plietker, Bernd
supporting information; experimental part, p. 5544 - 5547 (2011/12/05)
Different from most carbonates the allyloxy carbonyl protecting group can be cleaved under neutral conditions using metal catalysis. However, most of the catalysts employed to date are based upon precious metals. Herein we present two protocols for the mild Fe-catalyzed liberation of alcohols from allylcarbonates that are characterized by broad functional group tolerance and exclusive chemoselectivity.
Expanding the scope and orthogonality of PNA synthesis
Pothukanuri, Srinivasu,Pianowski, Zbigniew,Winssinger, Nicolas
supporting information; experimental part, p. 3141 - 3148 (2009/05/27)
Peptide nucleic acids (PNAs) hybridize to natural oligonucleotides according to Watson and Crick base-pairing rules. The robustness of PNA oligomers and ease of synthesis have made them an attractive platform to encode small or macromolecules for microarr
A bimetallic catalyst and dual role catalyst: Synthesis of N-(alkoxycarbonyl)indoles from 2-(alkynyl)phenylisocyanates
Kamijo, Shin,Yamamoto, Yoshinori
, p. 4764 - 4771 (2007/10/03)
3-Allyl-N-(alkoxycarbonyl)indoles are synthesized via the reaction of 2-(alkynyl)phenylisocyanates and allyl carbonates in the presence of Pd(PPh3)4 (1 mol %) and CuCl (4 mol %) bimetallic catalyst. It is most probable that Pd0