165673-74-5Relevant articles and documents
Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 11. 3-Hydroxycyprodime and Analogues: Opioid Antagonist Profile in Comparison to Cyprodime
Schmidhammer, Helmut,Jennewein, Herwig K.,Krassnig, Roland,Traynor, John R.,Patel, Dinesh,et al.
, p. 3071 - 3077 (2007/10/03)
A series of 3-hydroxy-substituted analogues (3-7) of the μ selective opioid antagonist cyprodime has been synthesized in order to evaluate the role of a hydroxy group at C-3 concerning μ opioid antagonist selectivity.Compounds 3-7 were tested in bioassays