166251-34-9 Usage
Description
3-(4-Fluoro-2-methyl-phenyl)-propionic acid, an organic compound with the chemical formula C10H11FO2, is a derivative of propionic acid. It is widely recognized for its role as a non-steroidal anti-inflammatory drug (NSAID), characterized by its analgesic, anti-inflammatory, and antipyretic properties. 3-(4-FLUORO-2-METHYL-PHENYL)-PROPIONIC ACID exerts its therapeutic effects by inhibiting the activity of cyclooxygenase-1 and cyclooxygenase-2 enzymes, which are pivotal in the synthesis of prostaglandins that mediate pain and inflammation.
Uses
Used in Pharmaceutical Industry:
3-(4-Fluoro-2-methyl-phenyl)-propionic acid is used as an active pharmaceutical ingredient for the development of medications aimed at relieving pain and reducing inflammation. Its application is particularly relevant in conditions such as arthritis, where it helps to alleviate the discomfort and swelling associated with the disease.
Additionally, it is utilized in formulations for menstrual cramps, providing relief from the pain and inflammation that can accompany this physiological process.
Used in Pain Management:
3-(4-Fluoro-2-methyl-phenyl)-propionic acid serves as a key component in pain management therapies, where its analgesic properties are leveraged to provide relief from various types of pain, including but not limited to musculoskeletal and postoperative pain.
Used in Antipyretic Treatments:
In the context of fever management, 3-(4-Fluoro-2-methyl-phenyl)-propionic acid is used as an antipyretic agent to reduce elevated body temperatures, thereby providing comfort and aiding in the recovery process from illnesses associated with fever.
Check Digit Verification of cas no
The CAS Registry Mumber 166251-34-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,2,5 and 1 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 166251-34:
(8*1)+(7*6)+(6*6)+(5*2)+(4*5)+(3*1)+(2*3)+(1*4)=129
129 % 10 = 9
So 166251-34-9 is a valid CAS Registry Number.
166251-34-9Relevant articles and documents
Synthesis method of succinic acid derivative or 3 -arylpropionic acid (by machine translation)
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Paragraph 0101-0114; 0115; 0137, (2020/10/30)
The invention discloses a synthesis method of a succinic acid derivative or 3 -arylpropionic acid, which comprises the following steps: adding a base in a drying reaction tube and CO removing CO. 2 The reaction is carried out under the irradiation of visible light, the reaction is carried out under visible light irradiation, and then separation and purification are carried out to obtain the butanedioic acid derivative or 3 -arylpropionic acid product; the base comprises sodium tert-butoxide, potassium tert-butoxide, lithium tert-butyl alcohol and 4 - potassium carbonate; and the reaction substrate comprises an acrylate compound or an aryl vinyl compound. CO can be induced by visible light. 2 The scheme provided by the invention is mild in reaction condition and wide in reaction 3 - substrate selectivity, and the reaction substrate is wide in selectivity, the raw materials are cheap and easily available, and the method has a good industrial application prospect. (by machine translation)
Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity
Musso, David L.,Orr, G. Faye,Cochran, Felicia R.,Kelley, James L.,Selph, Jeffrey L.,Rigdon, Greg C.,Cooper, Barrett R.,Jones, Michael L.
, p. 409 - 416 (2007/10/03)
Extension of the structure-activity relationship studies that led to the discovery of the nonsedating potent muscle relaxant, antiinflammatory, and analgesic agent (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1, has given rise to (E)-2-(4-chloro-6-fluoro
