166519-14-8

Basic information

• Product Name: 2-(bromomethyl)-1,3,5-triisopropylbenzene
• Synonyms: 2-(bromomethyl)-1,3,5-triisopropylbenzene
• CAS NO: 166519-14-8
• Molecular Weight: 297.279
• Mol File: 166519-14-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-(bromomethyl)-1,3,5-triisopropylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(bromomethyl)-1,3,5-triisopropylbenzene(166519-14-8)
• EPA Substance Registry System: 2-(bromomethyl)-1,3,5-triisopropylbenzene(166519-14-8)

Safety Data

• Hazardous Substances Data: 166519-14-8(Hazardous Substances Data)

Upstream product

• 4276-88-4 [2,4,6-tris(1-methylethyl)phenyl]methanol 
• 21524-34-5 2,4,6-triisopropyl-1-bromobenzene 
• 57199-00-5 2,4,6-triisopropylbenzoyl chloride 

Downstream Products

• 627503-45-1 (S)-3,3-bis(2,4,6-triisopropylphenylmethyl)-8,8-dimethyl-7-oxa-1-azabicyclo[3.3.0]octan-2-one 
• 627503-51-9 (S)-3,3-bis(2,4,6-triisopropylphenylmethyl)-5-hydroxymethylpyrrolidin-2-one 
• 627503-75-7 (S)-1-[4,4-bis(2,4,6-triisopropylphenylmethyl)-2-chloromethylpyrrolidin-1-yl]-2,2-dimethylpropan-1-one 
• 627503-71-3 (S)-1-[4,4-bis(2,4,6-triisopropylphenylmethyl)-2-hydroxymethylpyrrolidin-1-yl]-2,2-dimethylpropan-1-one 
• 54789-62-7 triphenyl(2,4,6-triisopropylbenzyl)phosphonium bromide 
• 1417619-03-4 C₃₅H₄₇N₂⁽¹⁺⁾*Br^(1-) 
• 1615212-43-5 C₂₇H₃₂N₂ 
• 1908442-13-6 3-(t-butyl)-4-(2,6-dimethoxyphenyl)-2-(2,4,6-triisopropylbenzyl)-2,3dihydrobenzo[d][1,3]oxaphosphole 

Relevant articles and documents

Inhibitors of acyl-CoA:Cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: An acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets

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HandaPhos: A General Ligand Enabling Sustainable ppm Levels of Palladium-Catalyzed Cross-Couplings in Water at Room Temperature

The new monophosphine ligand HandaPhos has been identified such that when complexed in a 1:1 ratio with Pd(OAc)2, enables Pd-catalyzed cross-couplings to be run using ≤1000 ppm of this pre-catalyst. Applications to Suzuki-Miyaura reactions involving highly funtionalized reaction partners are demonstrated, all run using environmentally benign nanoreactors in water at ambient temperatures.

Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) as hypocholesterolemic agents: Synthesis and structure-activity relationships of novel series of sulfonamides, acylphosphonamides and acylphosphoramidates

Sulfoacetic acid, phosphoramidate, and phosphonamide analogs of the ACAT inhibitors, CI-999 and CI-1011 were synthesized. The structure-activity relationships of these compounds as ACAT inhibitors are described.