16714-26-4

Basic information

• Product Name: Ethanone, 1-(2-azidophenyl)-
• CAS NO: 16714-26-4
• Molecular Formula: C8H7N3O
• Molecular Weight: 161.163
• Mol File: 16714-26-4.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(2-azidophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-azidophenyl)-(16714-26-4)
• EPA Substance Registry System: Ethanone, 1-(2-azidophenyl)-(16714-26-4)

Safety Data

• Hazardous Substances Data: 16714-26-4(Hazardous Substances Data)

Upstream product

• 1885-29-6 anthranilic acid nitrile 
• 577-59-3 2-acetylnitrobenzene 
• 7664-93-9 sulfuric acid 
• 41608-06-4 4-methyl-1,2,3-benzotriazine 3-oxide 
• 10026-13-8 phosphorus pentachloride 
• 7719-12-2 phosphorus trichloride 
• 67-66-3 chloroform 
• 551-93-9 2-aminoacetophenone 

Downstream Products

• 551-93-9 2-aminoacetophenone 
• 3260-61-5 indolin-3-one 
• 480-93-3 indoxyl 
• 4127-53-1 3-methylbenzo[c]isoxazole 
• 1220997-84-1 2-(2-azidophenyl)-4-phenylbut-3-yn-2-ol 

Relevant articles and documents

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Azacyclic derivative as well as preparation method and medical use thereof

The invention relates to an azacyclic derivative as well as a preparation method and medical use thereof and particularly relates to an azacyclic derivative represented by a general formula (I) (shownin the description), a preparation method thereof, a pharmaceutical composition containing the derivative and use of the derivative as an SMO antagonist, particularly in the treatment of diseases such as cancer related to Hedgehog signal channels. The definitions of groups in the general formula (I) are same as the definitions in the description.

Gold-catalyzed cyclization of 1-(2′-Azidoaryl) propynols: Synthesis of polysubstituted 4-quinolones

An unprecedented gold-catalyzed procedure for the synthesis of polysubstituted 4-quinolones from 1-(2′-Azidoaryl) propynols is described. The reaction undergoes an intramolecular nucleophilic attack of the azide group to the Au-Activated triple bonds in a 6-endo-dig manner and subsequent gold-Assisted expulsion of N2 to furnish an α-imino gold carbene intermediate, which triggers a 1,2-carbon migration and finally is converted to 2,3-disubstituted 4-quinolone.