1672-58-8 Usage
Description
N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide, also known as a metabolite of Dipyrone, is a pyrazolone derivative characterized by the presence of a formaylamino group at position 4, methyl groups at positions 1 and 5, and a phenyl group at position 2. It is a light tan solid and is derived from aminophenazone, a nonsteroidal anti-inflammatory drug.
Uses
Used in Pharmaceutical Industry:
N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide is used as an intermediate compound for the synthesis of various pharmaceutical products due to its structural properties and origin as a metabolite of Dipyrone, a nonsteroidal anti-inflammatory drug. Its role in the pharmaceutical industry is to serve as a building block for the development of new medications with potential anti-inflammatory and analgesic properties.
Used in Research and Development:
In the field of research and development, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide is utilized as a key compound for studying the structure-activity relationships of pyrazolone derivatives. This helps scientists understand the molecular mechanisms underlying their biological activities and potentially leads to the discovery of new drugs with improved efficacy and safety profiles.
Used in Quality Control and Analytical Chemistry:
N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide can be employed as a reference material in quality control and analytical chemistry for the validation of analytical methods and the determination of the purity and stability of related compounds. Its light tan solid form makes it suitable for various analytical techniques, such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS).
Check Digit Verification of cas no
The CAS Registry Mumber 1672-58-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,7 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1672-58:
(6*1)+(5*6)+(4*7)+(3*2)+(2*5)+(1*8)=88
88 % 10 = 8
So 1672-58-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N3O2/c1-9-11(13-8-16)12(17)15(14(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3,(H,13,16)
1672-58-8Relevant articles and documents
IDENTIFICATION OF IMPURITIES IN TECHNICAL-GRADE AMIDOPYRINE BY MASS-SPECTROMETRIC METHODS
Ermakov, A. I.,Pleshkova, A. P.,Voronin, V. G.,Voznesenskii, V. N.,Aleshina, V. A.,et al.
, p. 422 - 426 (1985)
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Oxidative degradation of sulpyrine by molecular oxygen
Yoshioka,Ogata,Shibazaki,Ejima
, p. 81 - 86,84,85 (1979)
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SYNTHESIS OF PHEROMONE DERIVATIVES VIA Z-SELECTIVE OLEFIN METATHESIS
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Paragraph 0240-0247; 0250-0251; 0262, (2021/12/28)
Disclosed herein are methods for synthesizing fatty olefin metathesis products of high Z-isomeric purity from olefin feedstocks of low Z-isomeric purity. The methods include contacting a contacting an olefin metathesis reaction partner, such as acylated alkenol or an alkenal acetal, with an internal olefin in the presence of a Z-selective metathesis catalyst to form the fatty olefin metathesis product. In various embodiments, the fatty olefin metathesis products are insect pheromones. Pheromone compositions and methods of using them are also described.
Method for synthesizing grassland spodoptera litura sex pheromone active ingredients
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, (2020/07/02)
The invention belongs to the technical field of green pesticide synthesis, and discloses a novel method for synthesizing grassland spodoptera litura sex pheromone active ingredients (Z)-9-dodecene-1-alcohol acetate, (Z)-9-tetradecene-1-alcohol acetate and (Z)-11-hexadecene-1-alcohol acetate. The method comprises the steps: using bromo-alcohol as a starting raw material; and firstly generating hydroxyl phosphonium salt with triphenylphosphine, then respectively carrying out Wittig coupling reaction with propionaldehyde and valeraldehyde to generate Z-type enol, and finally carrying out acetylation reaction with acetic anhydride to prepare (Z)-9-dodecene-1-alcohol acetate, (Z)-9-tetradecene-1-alcohol acetate and (Z)-11-hexadecene-1-alcohol acetate. According to the method, hydroxyl phosphonium salt is used for Wittig reaction, two steps of hydroxyl protection and deprotection are omitted, the synthetic route is simplified, and the method has the advantages of being environmentally friendly and the like.
