168886-97-3

Basic information

• Product Name: (2-Bromo-3-methylphenyl)methanol
• Synonyms: (2-Bromo-3-methylphenyl)methanol;2-bromo-3-methylbenzyl alcohol
• CAS NO: 168886-97-3
• Molecular Formula: C₈H₉BrO
• Molecular Weight: 201.06046
• Mol File: 168886-97-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 277.315°C at 760 mmHg
• Flash Point: 121.516°C
• Appearance: /
• Density: 1.482g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.581
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 14.22±0.10(Predicted)
• CAS DataBase Reference: (2-Bromo-3-methylphenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Bromo-3-methylphenyl)methanol(168886-97-3)
• EPA Substance Registry System: (2-Bromo-3-methylphenyl)methanol(168886-97-3)

Safety Data

• Hazardous Substances Data: 168886-97-3(Hazardous Substances Data)

Usage

General Description

(2-Bromo-3-methylphenyl)methanol is an organic compound that belongs to the class of phenols and benzene derivatives. It is a white crystalline solid with the chemical formula C8H9BrO, and is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. (2-Bromo-3-methylphenyl)methanol is also utilized as a reagent in organic synthesis, particularly in the formation of carbon-carbon bonds and substitution reactions. It has been reported to exhibit antimicrobial and anti-inflammatory properties, making it a potential candidate for the development of new drugs. However, it is important to handle this compound with caution, as it poses certain health and safety risks due to its toxic and irritating nature.

InChI:InChI=1/C8H9BrO/c1-6-3-2-4-7(5-10)8(6)9/h2-4,10H,5H2,1H3

Upstream product

• 53663-39-1 3-methyl-2-bromobenzoic acid 
• 131001-86-0 methyl 2-bromo-3-methylbenzoate 
• 155694-83-0 2-bromo-3-methylbenzoic acid ethyl ester 

Downstream Products

• 109179-31-9 2-bromo-3-methyl-benzaldehyde 
• 1285506-65-1 C₁₁H₁₁BrO₂ 
• 1285506-66-2 C₁₂H₁₄BrN₃O 
• 1319194-45-0 6-(2-((2-chloro-5-(trifluoromethyl)phenoxy)methyl)-6-methylphenyl)-3-morpholinoquinolin-2-amine 
• 1319196-88-7 2-bromo-1-((2-chloro-5-(trifluoromethyl)phenoxy)methyl)-3-methylbenzene 
• 1383673-48-0 1,2-bis(2-bromo-3-methylphenyl)ethene 
• 66790-58-7 2-bromo-1-(bromomethyl)-3-methylbenzene 
• 632-46-2 2,6-dimethylbenzoic acid 
• 115740-36-8 2-bromo-1-(methoxymethyl)-3-methylbenzene 

Relevant articles and documents

5-MEMBERED HETEROARYLAMINOSULFONAMIDES FOR TREATING CONDITIONS MEDIATED BY DEFICIENT CFTR ACTIVITY

The invention relates to heteroaryl compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.

Site- and regio-selective incorporation of carbon dioxide into the C(sp2)Si bond of benzosilacyclobutenes

A reaction of benzosilacyclobutenes with carbon dioxide is catalyzed by a nickel complex having an N-heterocyclic carbene ligand. Carbon dioxide inserts into the C(sp2)Si bond in a site- and regio-selective manner to form a carboncarbon bond, furnishing benzoic acid derivatives.

Rh(III)-Catalyzed Phosphine Oxide Migration Reactions: Selective Synthesis of 3-Phosphinoylindoles

3-Phosphinoylindoles are important components of biological active natural products and materials in pharmaceuticals. Herein, a new approach for the synthesis of 3-phosphinoylindoles has been established by a Rh(III)-catalyzed cyclization from readily acc