169114-07-2

Basic information

• Product Name: N-(4-(bromomethyl)phenyl)-N-methylacetamide
• Synonyms: N-(4-(bromomethyl)phenyl)-N-methylacetamide
• CAS NO: 169114-07-2
• Molecular Weight: 242.115
• Mol File: 169114-07-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-(4-(bromomethyl)phenyl)-N-methylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(bromomethyl)phenyl)-N-methylacetamide(169114-07-2)
• EPA Substance Registry System: N-(4-(bromomethyl)phenyl)-N-methylacetamide(169114-07-2)

Safety Data

• Hazardous Substances Data: 169114-07-2(Hazardous Substances Data)

Upstream product

• 103-89-9 4-Methylacetanilide 
• 106-49-0 p-toluidine 
• 612-03-3 4-(N-methylacetamido)toluene 
• 169114-06-1 N-(4-(hydroxymethyl)phenyl)-N-methylacetamide 

Downstream Products

• 64563-12-8 C₁₉H₂₆N₂O₆ 

Relevant articles and documents

Carbocation Catalyzed Bromination of Alkyl Arenes, a Chemoselective sp3 vs. sp2 C?H functionalization.

The versatility of the trityl cation (TrBF4) as a highly efficient Lewis acid organocatalyst is demonstrated in a light induced benzylic brominaion of alkyl-arenes under mild conditions. The reaction was conducted at ambient temperature under common hood light (55 W fluorescent light) with catalyst loadings down to 2.0 mol% using N-bromosuccinimide (NBS) as the brominating agent. The protocol is applicable to an extensive number of substrates to give benzyl bromides in good to excellent yields. In contrast to most previously reported strategies, this protocol does not require any radical initiator or extensive heating. For electron-rich alkyl-arenes, the trityl ion catalyzed bromination could be easily switched between benzylic sp3 C?H functionalization and arene sp2 C?H functionalization by simply alternating the solvent. This chemoselective switch allows for high substrate control and easy preparation of benzyl bromides and bromoarenes, respectively. The chemoselective switch was also applied in a one-pot reaction of 1-methylnaphthalene for direct introduction of both sp3 C?Br and sp2 C?Br functionality. (Figure presented.).

Mild chemical and biological synthesis of donor-acceptor flanked reporter stilbenes: Demonstration of a physiological wittig olefination reaction

Unprecedented chemoselectivity is reported for the Wittig olefination reaction leading to the formation of reporter stilbenes under physiological conditions.

Pyran-4-ylmethyl substituted arylalkylaryl-, arylalkenylylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase

Compounds of structure STR1 where W is selected from STR2 where Q is oxygen or sulfur, R5 and R6 are independently selected from hydrogen and alkyl, or R5 and R6, together with the nitrogen atoms to which they a