169217-47-4 Usage
General Description
1,2-Propanediol,1-(3-chloro-4-methoxyphenyl)-, (1R,2S)- is a chemical compound with the molecular formula C9H11O4Cl. Also known as dexketoprofen, it is an active ingredient in non-steroidal anti-inflammatory drugs (NSAIDs) and is used for its pain-relieving and anti-inflammatory properties. Dexketoprofen is commonly administered as a tablet or injection to treat moderate to severe pain, such as that caused by arthritis, dental procedures, and sports injuries. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. However, like other NSAIDs, dexketoprofen can have side effects, including stomach ulcers, gastrointestinal bleeding, and kidney problems, and it should be used with caution, especially in older adults and those with certain medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 169217-47-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,2,1 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 169217-47:
(8*1)+(7*6)+(6*9)+(5*2)+(4*1)+(3*7)+(2*4)+(1*7)=154
154 % 10 = 4
So 169217-47-4 is a valid CAS Registry Number.
169217-47-4Relevant articles and documents
Synthesis of (1R,2S)-1-(3′-chloro-4′-methoxyphenyl)-1,2- propanediol (trametol) and (1R,2S)-1-(3′,5′-dichloro-4′- methoxyphenyl)-1,2-propanediol, chlorinated fungal metabolites in the natural environment
Kousaka, Takeshi,Mori, Kenji
, p. 697 - 701 (2007/10/03)
(1R,2S)-1-(3′-Chloro-4′-methoxyphenyl)-1,2-propanediol (Trametol, 3), a metabolite of the fungus Trametes sp. IVP-F640 and Bjerkandera sp. BOS55, was synthesized by employing Sharpless asymmetric dihydroxylation as the key step. Similarly, the (1R,2S)-isomer of 1-(3′,5′-dichloro- 4′-methoxyphenyl)-1,2-propanediol (4), another metabolite of Bjerkandera sp. BOS55, was synthesized by asymmetric dihydroxylation.
