170512-14-8 Usage
Description
25-Hydroxyvitamin D3 3-Glucuronide is a glucuronidated conjugate of 5-Hydroxyvitamin D3 (C125700), which is the principal circulating form of vitamin D3. 25-HydroxyvitaMin D3 3-Glucuronide is formed in the liver through hydroxylation at the C-25 position and plays a crucial role in regulating calcium levels in the body.
Uses
Used in Pharmaceutical Industry:
25-Hydroxyvitamin D3 3-Glucuronide is used as a calcium regulator for maintaining proper calcium homeostasis in the body. It is essential for various physiological processes, including bone metabolism, immune system function, and cellular differentiation.
Used in Nutritional Supplements:
As a vital component of vitamin D3, 25-Hydroxyvitamin D3 3-Glucuronide is used in the development of nutritional supplements to ensure adequate levels of this essential nutrient in the human diet. This helps in preventing vitamin D deficiency and its associated health issues, such as rickets, osteoporosis, and immune system dysfunction.
Used in Research and Development:
25-Hydroxyvitamin D3 3-Glucuronide is also utilized in research and development for studying the role of vitamin D in various biological processes and its potential therapeutic applications in treating diseases related to calcium metabolism and immune function.
Check Digit Verification of cas no
The CAS Registry Mumber 170512-14-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,5,1 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 170512-14:
(8*1)+(7*7)+(6*0)+(5*5)+(4*1)+(3*2)+(2*1)+(1*4)=98
98 % 10 = 8
So 170512-14-8 is a valid CAS Registry Number.
170512-14-8Relevant articles and documents
In vitro glucuronidation of 25-hydroxyvitamin D3 and its pro-form
Shimada, Kazutake,Kamezawa, Yuko,Mitamura, Kuniko
, p. 596 - 600 (1997)
In vitro glucuronidation of 25-hydroxyvitamin D3 and its pro-form has been investigated by means of HPLC with UV detection. Although both substrates gave 3- and 25-glucuronides in the presence of the rat liver microsomal fraction and uridine-5'
