174456-32-7

Basic information

• Product Name: 2'-(β-D-glucopyranosyloxy)-6'-hydroxy-3-(5-benzo[b]-furanyl)propiophenone
• Synonyms: 2'-(β-D-glucopyranosyloxy)-6'-hydroxy-3-(5-benzo[b]-furanyl)propiophenone
• CAS NO: 174456-32-7
• Molecular Weight: 444.438
• Mol File: 174456-32-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2'-(β-D-glucopyranosyloxy)-6'-hydroxy-3-(5-benzo[b]-furanyl)propiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-(β-D-glucopyranosyloxy)-6'-hydroxy-3-(5-benzo[b]-furanyl)propiophenone(174456-32-7)
• EPA Substance Registry System: 2'-(β-D-glucopyranosyloxy)-6'-hydroxy-3-(5-benzo[b]-furanyl)propiophenone(174456-32-7)

Safety Data

• Hazardous Substances Data: 174456-32-7(Hazardous Substances Data)

Upstream product

• 13494-80-9 hydrogen telluride 
• 10035-16-2 benzofuran-5-carbaldehyde 
• 23141-00-6 2',6'-dihydroxyacetophenone 2'-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside) 
• 174456-38-3 2'-(2,3-di-O-Acetyl-β-D-glucopyranosyloxy)-6'-hydroxy-3-(5-benzo[b]-furanyl)propiophenone 

Downstream Products

• 174456-59-8 2'-(2,3-di-O-acetyl-4,6-O-benzylidene-β-D-glucopyranosyloxy)-6'-acetoxy-3-(5-benzo-[b]furanyl)propiophenone 
• 174456-60-1 2'-(2,3-di-O-acetyl-4,6-O-benzylidene-β-D-glucopyranosyloxy)-6'-hydroxy-3-(5-benzo[b]furanyl)propiophenone 
• 189576-63-4 6'-acetoxy-2-(benzofuran-5-yl)-2'-hydroxypropiophenone 2'-O-(2,3-O-diacetyl-6-O-methoxymethyl-β-D-glucopyranoside) 
• 217634-89-4 Carbonic acid (2R,3S,4S,5R,6S)-6-[3-allyloxy-2-(3-benzofuran-5-yl-propionyl)-phenoxy]-3,4,5-trihydroxy-tetrahydro-pyran-2-ylmethyl ester methyl ester 
• 174456-37-2 2'-(2,3-di-O-acetyl-β-D-glucopyranosyloxy)-6'-acetoxy-3-(5-benzo[b]furanyl)propiophenone 
• 174456-38-3 2'-(2,3-di-O-Acetyl-β-D-glucopyranosyloxy)-6'-hydroxy-3-(5-benzo[b]-furanyl)propiophenone 
• 217634-73-6 6'-allyloxy-2-(benzofuran-5-yl)-2'-hydroxypropiophenone 2'-O-β-D-glucopyranoside 

Relevant articles and documents

Propiophenone derivative and a process for preparing the same

A propiophenone derivative of the formula ?I!: STR1 wherein X is O, S or methylene, OY is a protected or unprotected OH, Z is β-D-glucopyranosyl or 4-O-(α-D-glucopyranosyl)-β-D-glucopyranosyl or wherein one or more hydroxy groups of these groups may optionally be acylated, and the dotted line means the presence or absence of a double bond, or a pharmaceutically acceptable salt thereof. Said compounds have excellent hypoglycemic activity so that they are useful in the prophylaxis or treatment of diabetes.

Na+-glucose cotransporter inhibitors as antidiabetic agents. II. Synthesis and structure-activity relationships of 4'-dehydroxyphlorizin derivatives

A novel series of 4'-dehydroxyphlorizin derivatives was synthesized and the effects of these compounds on urinary glucose excretion were evaluated in rats. There was a strict structural requirement for activity. Introduction of a small substituent or a fi