174464-39-2

Basic information

• Product Name: BOC-An^pGlu ethylene dithioketal Ile-OCH₃
• Synonyms: BOC-An^pGlu ethylene dithioketal Ile-OCH₃
• CAS NO: 174464-39-2
• Molecular Weight: 540.745
• Mol File: 174464-39-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: BOC-An^pGlu ethylene dithioketal Ile-OCH₃(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-An^pGlu ethylene dithioketal Ile-OCH₃(174464-39-2)
• EPA Substance Registry System: BOC-An^pGlu ethylene dithioketal Ile-OCH₃(174464-39-2)

Safety Data

• Hazardous Substances Data: 174464-39-2(Hazardous Substances Data)

Upstream product

• 174464-32-5 tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-5-<2,2-(1,3-dithiolanyl)>-5-(4-methoxyphenyl)pentanoate 
• 174464-30-3 tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-5-<2,2-(1,3-dioxolanyl)>-5-(4-methoxyphenyl)pentanoate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 2577-46-0 L-isoleucine methyl ester 
• 174464-37-0 (S)-2-((tert-butoxycarbonyl)amino)-5-<2,2-(1,3-dithiolanyl)>-5-(4-methoxyphenyl)pentanoic acid 

Downstream Products

• 174464-45-0 BOC-Met-An^pGlu-Ile-OCH₃ 
• 174464-43-8 BOC-Met-An^pGlu ethylene dithioketal Ile-OCH₃ 

Relevant articles and documents

Synthesis of anisolylated aspartyl and glutamyl tripeptides

A process has been developed for transforming the β-carboxyl of aspartate and the γ-carboxyl of glutamate into anisolyl ketones. These ketones are occasional byproducts in peptide synthesis, resulting from deprotection or resin-removal processes in the presence of anisole as a scavenger. The ketone amino acids have been incorporated in a tripeptide by coupling with CBMIT. During peptide bond formation the keto group of the glutamyl residue required protection, which was provided as the ethylene dithioketal.