174665-87-3Relevant articles and documents
Nonpeptide α(v)β3 antagonists. 1. Transformation of a potent, integrin-selective α(IIb)β3 antagonist into a potent α(v)β3 antagonist
Duggan,Duong,Fisher,Hamill,Hoffman,Huff,Ihle,Leu,Nagy,Perkins,Rodan,Wesolowski,Whitman,Zartman,Rodan,Hartman
, p. 3736 - 3745 (2007/10/03)
Modification of the potent fibrinogen receptor (α(IIb)β3) antagonist 1 generated compounds with high affinity for the vitronectin receptor α(v)β3. Sequential modification of the basic N-terminus of 1 led to the identification of the