174869-04-6

Basic information

• Product Name: α-(2-cyanoethyl)-4,4'-dimethoxybenzoin
• Synonyms: α-(2-cyanoethyl)-4,4'-dimethoxybenzoin
• CAS NO: 174869-04-6
• Molecular Weight: 325.364
• Mol File: 174869-04-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: α-(2-cyanoethyl)-4,4'-dimethoxybenzoin(CAS DataBase Reference)
• NIST Chemistry Reference: α-(2-cyanoethyl)-4,4'-dimethoxybenzoin(174869-04-6)
• EPA Substance Registry System: α-(2-cyanoethyl)-4,4'-dimethoxybenzoin(174869-04-6)

Safety Data

• Hazardous Substances Data: 174869-04-6(Hazardous Substances Data)

Upstream product

• 119-52-8 4,4'-dimethoxybenzoin 
• 107-13-1 acrylonitrile 

Downstream Products

• 55234-56-5 4-(4-methoxy-phenyl)-4-oxo-butyronitrile 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant articles and documents

Synthesis of ketones by retro-benzoin condensation catalyzed by potassium cyanide

The treatment of 2-benzyl-1,2-diphenyl-2-hydroxyethanone (3a, benzylbenzoin) with potassium cyanide in DMF gave deoxybenzoin (4a). The formation of deoxybenzoin (4a) proceeds through retro-benzoin condensation by catalytic action of cyanide ion. Similarly, retro-benzoin condensation applied to several substituted benzoins 3 resulted in the formation of the corresponding ketones 4 in excellent yields.