175135-01-0

Basic information

• Product Name: 2-PHENOXYPYRIDINE-3-CARBOHYDRAZIDE
• Synonyms: 2-PHENOXYPYRIDINE-3-CARBOHYDRAZIDE;2-PHENOXYPYRIDINE-3-CARBOXYLIC ACID HYDRAZIDE;2-Phenoxynicotinohydrazide
• CAS NO: 175135-01-0
• Molecular Formula: C₁₂H₁₁N₃O₂
• Molecular Weight: 229.23464
• Mol File: 175135-01-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 161-163°C
• Appearance: /
• CAS DataBase Reference: 2-PHENOXYPYRIDINE-3-CARBOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENOXYPYRIDINE-3-CARBOHYDRAZIDE(175135-01-0)
• EPA Substance Registry System: 2-PHENOXYPYRIDINE-3-CARBOHYDRAZIDE(175135-01-0)

Safety Data

• Hazardous Substances Data: 175135-01-0(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 35620-71-4 2-phenoxypyridine-3-carboxylic acid 
• 1254691-84-3 ethyl 2-phenoxypyridine-3-carboxylate 
• 2942-59-8 2-chloronicotinic acid 

Downstream Products

• 474973-39-2 2-Phenoxypyridine-3-carboxylic acid (3-trifluoromethylbenzylidene)-hydrazide 
• 474973-44-9 2-phenoxy-N'-(pyridin-4-ylmethylidene)nicotinic acid hydrazide 
• 474973-43-8 2-phenoxy-N'-(pyridin-3-ylmethylidene)nicotinic acid hydrazide 
• 1254691-92-3 2-phenoxy-N'-(thiophen-2-ylmethylidene)nicotinic acid hydrazide 
• 1254691-87-6 (4-methylbenzylidene)-2-phenoxynicotinic acid hydrazide 
• 1254691-90-1 (4-nitrobenzylidene)-2-phenoxynicotinic acid hydrazide 
• 474973-64-3 benzylidene-2-phenoxynicotinic acid hydrazide 
• 1254691-89-8 (4-dimethylaminobenzylidene)-2-phenoxynicotinic acid hydrazide 
• 1254691-91-2 (2,4-dimethoxybenzylidene)-2-phenoxynicotinic acid hydrazide 
• 1254692-04-0 (1-(4-methoxyphenyl)ethylidene)-2-phenoxynicotinic acid hydrazide 
• 395-64-2 2,5-bis(trifluoromethyl)benzaldehyde 
• 134099-28-8 3-trifluoromethyl-4,5-difluorobenzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 401-95-6 3,5-Bis(trifluoromethyl)benzaldehyde 

Relevant articles and documents

Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents

A series of 2-phenoxynicotinic acid hydrazides were synthesized and evaluated for their analgesic and anti-inflammatory activities. Several compounds having an unsubstituted phenyl/4-pyridyl or C-4 methoxy substituent on the terminal phenyl ring showed moderate to high analgesic or antiinflammatory activity in comparison to mefenamic acid as the reference drug. The compounds with highest anti-inflammatory activity were subjected to in vitro COX-1/COX-2 inhibition assays and showed moderate to good COX-1 and weak COX-2 inhibition activities.