175277-96-0 Usage
General Description
4-CYANO-2-(TRIFLUOROMETHYL)ACETANILIDE is a chemical compound with the molecular formula C10H8F3N3O. It is a white powder with a molecular weight of 237.18 g/mol. 4-CYANO-2-(TRIFLUOROMETHYL)ACETANILIDE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique structure makes it a versatile building block for the production of various biologically active compounds. Additionally, it is also used as a reagent in organic synthesis and as a raw material for the production of dyes and pigments. However, it is important to handle this compound with care as it is known to be a potential irritant to the skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 175277-96-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,7 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 175277-96:
(8*1)+(7*7)+(6*5)+(5*2)+(4*7)+(3*7)+(2*9)+(1*6)=170
170 % 10 = 0
So 175277-96-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H7F3N2O/c1-6(16)15-9-3-2-7(5-14)4-8(9)10(11,12)13/h2-4H,1H3,(H,15,16)
175277-96-0Relevant articles and documents
Visible-light-induced Pd-catalyzed: Ortho -trifluoromethylation of acetanilides with CF3SO2Na under ambient conditions in the absence of an external photocatalyst
Zou, Long,Li, Pinhua,Wang, Bin,Wang, Lei
supporting information, p. 3737 - 3740 (2019/04/01)
A visible-light-induced Pd-catalyzed ortho-trifluoromethylation of acetanilides with CF3SO2Na was developed. The reaction proceeded smoothly at room temperature in air without any external photocatalyst or additive, providing the desired products in moderate to good yields with good functional group tolerance and regioselectivity.
Copper-free direct C-H trifluoromethylation of acetanilides with sodium trifluoromethanesulfinate
Wu, Mingxi,Ji, Xinfei,Dai, Wenpeng,Cao, Song
, p. 8984 - 8989 (2015/01/09)
A copper-free direct C-H ortho trifluoromethylation of electron-deficient 4-substituted acetanilides using Langlois reagent (NaSO2CF3) as the CF3 source in the presence of tert-butyl hydroperoxide (tBuOOH, TBHP) was developed.
