17893-94-6

Basic information

• Product Name: 3-Methylnaphthalene-2-carboxaldehyde
• Synonyms: 3-Methylnaphthalene-2-carboxaldehyde
• CAS NO: 17893-94-6
• Molecular Formula: C12H10O
• Molecular Weight: 170.2072
• Mol File: 17893-94-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Methylnaphthalene-2-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methylnaphthalene-2-carboxaldehyde(17893-94-6)
• EPA Substance Registry System: 3-Methylnaphthalene-2-carboxaldehyde(17893-94-6)

Safety Data

• Hazardous Substances Data: 17893-94-6(Hazardous Substances Data)

Upstream product

• 939-15-1 2-bromo-3-methylnaphthalene 
• 68-12-2 N,N-dimethyl-formamide 
• 66-99-9 β-naphthaldehyde 
• 581-40-8 2,3-dimethylnaphthalene 
• 88802-94-2 Lithium; (4-methyl-piperazin-1-yl)-naphthalen-2-yl-methanolate 
• 74-88-4 methyl iodide 
• 64-19-7 acetic acid 
• 39171-57-8 2-Bromomethyl-3-methylnaphthalene 

Downstream Products

• 39110-32-2 3-hydroxynaphthalene-2-carboxylic acid 
• 31554-16-2 2-hydroxymethyl-3-methylnaphthalene 
• 39110-33-3 3-Methyl-2-naphthaldehyd-2,4-dinitrophenylhydrazon 

Relevant articles and documents

Principal Component-Three Component Self-Modeling Analysis Applied to trans-1,2-Di(2-naphthyl)ethene Fluorescence

Fluorescence spectra of trans-1,2-di(2-naphthyl)ethene, DNE, obtained under varying conditions of excitation wavelength and oxygen and carbon tetrachloride concentrations in methylcyclohexane were resolved into three distinct components by application of principal component analysis combined with a three-component self-modeling technique.Spectral matrices for O2 and CCl4 quenching, treated separately, yielded nearly identical pure component fluorescence spectra.The spectra were assigned to each of the three conformers of DNE by comparison with spectra of 3-methyl derivatives.Stern-Volmer quenching plots for the individual conformers were shown to be independent of excitation wavelength, indicating that each conformer has a single lifetime.

PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to pyrimidine derivatives of formula (I) wherein (R1)n, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (II) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.

PREPARATION OF NAPHTHALDEHYDES BY CERIUM(IV)AMMONIUM NITRATE OXIDATION OF METHYLNAPHTHALENES.

Naphthalenes with an Me group in the 1-position gave aldehydes in good to excellent yields when oxidized with cerium(IV) ammonium nitrate (CAN) in 50percent HOAc at 85 deg C.Under the same conditions methylnaphthalenes with no Me group in a peri position gave aldehydes in fair yields but also significant amounts of 1,4-naphthoquinone.