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179174-79-9

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179174-79-9 Usage

General Description

(Z)-4-acetoxy-3-(4-(Methylsulfonyl) phenyl)-2-phenylbut-2-enoic acid is a chemical compound with anti-inflammatory properties. It belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs) and is classified as a COX-2 inhibitor. (Z)-4-acetoxy-3-(4-(Methylsulfonyl) phenyl)-2-phenylbut-2-enoic acid works by inhibiting the production of prostaglandins, which are responsible for causing pain and inflammation in the body. It is commonly used to treat conditions such as arthritis, menstrual cramps, and other types of pain and inflammation. However, it may also present potential side effects and interactions with other drugs, so it should be used under the supervision of a healthcare professional.

Check Digit Verification of cas no

The CAS Registry Mumber 179174-79-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,1,7 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 179174-79:
(8*1)+(7*7)+(6*9)+(5*1)+(4*7)+(3*4)+(2*7)+(1*9)=179
179 % 10 = 9
So 179174-79-9 is a valid CAS Registry Number.

179174-79-9Relevant articles and documents

Synthesis of a NO-releasing prodrug of rofecoxib

Engelhardt, F. Conrad,Shi, Yao-Jun,Cowden, Cameron J.,Conlon, David A.,Pipik, Brenda,Zhou, George,McNamara, James M.,Dolling, Ulf-H.

, p. 480 - 491 (2007/10/03)

A newly developed synthesis of a NO-releasing prodrug of rofecoxib is described. The highly productive process consists of five chemical steps and produces prodrug 1 in an overall 64% yield from commercially available 3-phenyl-2-propyn-1-ol (4). The synth

Process for making nitric oxide releasing prodrugs of diaryl-2-(5H)-furanones as cyclooxygenase-2 inhibitors

-

Page/Page column 6-8, (2010/02/13)

The invention encompasses a novel process for making compounds of Formula I which are prodrugs of cyclooxygenase-2 selective inhibitors that convert in vivo to diaryl-2-(5H)-furanones and also liberate nitric oxide in vivo. As such, the compounds made by

Stilbene derivatives useful as cyclooxygenase-2 inhibitors

-

, (2008/06/13)

The invention encompasses novel compounds of Formula Iuseful in the treatment of cyclooxygenase-2 mediated diseases. STR1 The invention also encompasses certain pharmaceuticalcompositions and methods for treatment of cyclooxygenase-2 mediated diseases comprising the use of compounds of Formula I.

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