18150-94-2 Usage
Description
3-Nitro-2-phenylthiophene, with the molecular formula C10H7NO2S, is a nitro derivative of 2-phenylthiophene. It is a chemical compound known for its aromatic properties and is widely used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its versatile nature and potential applications make it an important compound in the field of chemical research.
Uses
Used in Pharmaceutical Industry:
3-Nitro-2-phenylthiophene is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of complex chemical structures. Its aromatic properties and potential biological activities, such as anticancer properties, make it a valuable component in the creation of new drugs.
Used in Agrochemical Industry:
3-Nitro-2-phenylthiophene is utilized as an intermediate in the synthesis of agrochemicals, particularly in the development of pesticides and other agricultural chemicals. Its aromatic nature and potential antimicrobial properties contribute to the effectiveness of these products in protecting crops and enhancing agricultural productivity.
Used in Organic Synthesis:
3-Nitro-2-phenylthiophene is used as a key component in organic synthesis for the production of other complex chemicals. Its versatile chemical structure allows for various reactions and modifications, making it a valuable building block in the synthesis of a wide range of organic compounds.
Used in Chemical Research:
3-Nitro-2-phenylthiophene is studied for its potential biological activities, such as its anticancer and antimicrobial properties. Researchers are exploring its applications in the development of new therapeutic agents and understanding its interactions with biological systems to enhance its potential uses in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 18150-94-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,1,5 and 0 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 18150-94:
(7*1)+(6*8)+(5*1)+(4*5)+(3*0)+(2*9)+(1*4)=102
102 % 10 = 2
So 18150-94-2 is a valid CAS Registry Number.
18150-94-2Relevant articles and documents
A one-pot synthesis of 3-nitrothiophene and 3-nitro-2-substituted thiophenes
McNabola, Neasa,O'Connor, Cornelius J.,Roydhouse, Mark D.,Wall, Michael D.,Southern, J. Mike
, p. 4598 - 4603 (2015/06/08)
A one-pot approach to the synthesis of 3-nitrothiophene and 3-nitro-2-substituted thiophenes has been developed. Exposure of 1,4-dithane-2,5-diol to nitroacetates or nitroalkenes in the presence of 25% triethylamine and subsequent treatment with molecular sieves and combinations of silica gel or acidic alumina with DDQ or chloranil formed 3-nitrothiophene or a number of 3-nitro-2-substituted thiophenes with complete regiocontrol. A simple work-up procedure removes the requirement for purification by chromatography for most post-synthetic applications.
A useful one-pot procedure for obtaining 2-aryl-5-nitrothiophenes from bromonitromethane and 3-aryl-3-chloro-propenals
Rodríguez-Domínguez, Juan C.,Thomae, David,Seck, Pierre,Kirsch, Gilbert
, p. 286 - 288 (2008/12/20)
A one-pot procedure was developed to prepare new 2-aryl-5-nitrothiophenes efficiently from bromonitromethane and 3-chloro-3-aryl-propenals. Nitrothiophenes were synthesized in good yields with a simple and easy workup procedure. Georg Thieme Verlag Stuttg
