182318-00-9 Usage
Description
1-(1H-benzo[d][1,2,3]triazol-1-yl)-2,2-diphenylethan-1-one, also known as BTT-1023, is a synthetic compound belonging to the class of organic compounds known as benzotriazoles. It is a diphenylethanone derivative with a chemical structure that features a benzotriazole ring attached to a diphenylethanone moiety. BTT-1023 has shown potential pharmaceutical properties and has been investigated for its use in treating various diseases, including autoimmune conditions and cancer. Its immunosuppressive and anti-inflammatory effects in preclinical studies make it a compound of interest for further research and development in medicinal chemistry and drug discovery.
Uses
Used in Pharmaceutical Industry:
1-(1H-benzo[d][1,2,3]triazol-1-yl)-2,2-diphenylethan-1-one is used as a potential therapeutic agent for autoimmune conditions and cancer due to its demonstrated immunosuppressive and anti-inflammatory effects in preclinical studies. 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2,2-diphenylethan-1-one's unique chemical structure and pharmacological properties make it a promising candidate for further research and development in the field of medicinal chemistry and drug discovery.
Used in Medicinal Chemistry Research:
1-(1H-benzo[d][1,2,3]triazol-1-yl)-2,2-diphenylethan-1-one is used as a subject of study for understanding its potential applications in the treatment of various diseases. Its chemical structure and pharmacological properties are of interest to researchers working on the development of new drugs and therapies for autoimmune conditions and cancer.
Used in Drug Discovery:
1-(1H-benzo[d][1,2,3]triazol-1-yl)-2,2-diphenylethan-1-one is used as a lead compound in the search for new therapeutic agents. Its potential pharmaceutical properties and demonstrated effects in preclinical studies make it a valuable starting point for the development of novel drugs targeting autoimmune conditions and cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 182318-00-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,3,1 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 182318-00:
(8*1)+(7*8)+(6*2)+(5*3)+(4*1)+(3*8)+(2*0)+(1*0)=119
119 % 10 = 9
So 182318-00-9 is a valid CAS Registry Number.
182318-00-9Relevant articles and documents
Sulfur–Fluoride Exchange (SuFEx)-Mediated Synthesis of Sterically Hindered and Electron-Deficient Secondary and Tertiary Amides via Acyl Fluoride Intermediates
Smedley, Christopher J.,Barrow, Andrew S.,Spiteri, Christian,Giel, Marie-Claire,Sharma, Pallavi,Moses, John E.
supporting information, p. 9990 - 9995 (2017/08/01)
Amide bond formation is one of the most executed reactions in chemistry and biology. This is largely due to the ubiquity of the amide functional group in biological molecules, natural products and pharmaceutically important drugs. We report here the development of “SuFExAmide”: a new sulfur–fluoride exchange (SuFEx) click chemistry based protocol for the efficient amidation of carboxylic acids via acyl fluoride intermediates. We have developed benzene-1,3-disulfonyl fluoride as a cost effective, powerful and versatile coupling agent, which delivers challenging secondary and tertiary amides in excellent yields from sterically hindered and electron-deficient amines. The straightforward method offers significant benefits over existing protocols in terms of substrate scope, efficiency and ease of operation and is demonstrated by the synthesis of 44 amides, including GNF6702, an antiprotozoal drug candidate. In the majority of cases, the amide products are obtained in high yield without the need for excess reagents or chromatographic purification.
